Sex differences and rheumatoid arthritis

Armen Hareyan's picture
Advertisement

Characterized by chronic synovial tissue inflammation, increasing erosions of cartilage and bone, and eventual destruction of joints, rheumatoid arthritis (RA) is a complex and confounding autoimmune disease. It is associated with a variety of genetic and environmental factors and known to strike women about three times as frequently as men. A major obstacle to investigating this clear sex bias has been the lack of a laboratory rat or mouse that mimics human RA. Until now.

Researchers at the Mayo Clinic have produced a new breed of transgenic mice with autoimmune responses similar to human

Share this content.

If you liked this article and think it may help your friends, consider sharing or tweeting it to your followers.
Advertisement