Rheumatoid Arthritis Could Be Prevented If The Timing Is Right
Patients diagnosed with 'undifferentiated rheumatoid' arthritis could actually have their disease outlook changed significantly if treatment is given at the right time, according to the results of a study presented at the Annual European Congress of Rheumatology on Wednesday 21 June, by Mrs. Henrike Van Dongen and her colleagues.
The PROMPT-study (Probable rheumatoid arthritis: Methotrexate versus Placebo Treatment-study) is a double-blind placebo controlled randomized multicenter trial in 110 patients with undifferentiated arthritis, which means they have arthritis but the exact diagnosis is undetermined. The aim of the study was to determine whether the patients would benefit from treatment with methotrexate (MTX). At the end of the study, patients were tested with a special antibody blood test (anti-cyclic citrullinated peptide antibody, anti-CCP) to confirm a diagnosis of Rheumatoid Arthritis, one of the most aggressive and debilitating forms of rheumatism.
The study concluded that, in the MTX group, fewer patients developed