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Drug Clinical Trials

Rigel Initiates Clinical Trial For Allergic Asthma

Pfizer has begun a Phase 1 clinical trial of an inhaled formulation of Rigel's small molecule syk kinase inhibitor, R343, for the treatment of allergic asthma. R343 is the third product candidate in Rigel's clinical portfolio.

Under the terms of the companies' 2005 collaboration agreement, Rigel will receive a $5 million milestone payment from Pfizer for the commencement of this study. Pfizer retains exclusive rights to R343 and is responsible for its clinical development.

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Lexicon Initiates Trial Of LX6171 Drug Candidate For Cognitive Disorders

Lexicon Pharmaceuticals commenced dosing in a Phase 2a clinical trial with LX6171, an oral drug candidate for the treatment of cognitive impairment associated with disorders such as Alzheimer's disease, schizophrenia, and vascular dementia.

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Raven Initiates Clinical Trial Of RAV12 Therapeutic Antibody For Adenocarcinomas Treatment

Raven biotechnologies is continuing to enroll new patients in the maximum tolerated dose cohort expansion segment of its Phase 1/2a trial for patients with cancers of the gastrointestinal tract that express the RAAG12 antigen.

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Clinical Trials Of Medications In Children Fall Short

Federal regulators in recent years have "enticed or forced pharmaceutical companies to conduct hundreds of studies that have produced vital results about more than 200 drugs," but physicians "still have scant information to guide them when they administer many medications to kids," the Washington Post reports. About two-thirds of medications administered to children remain untested in young age groups.

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