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Drug Clinical Trials

Spectral's EAA Used In Study For Sepsis Anti-Endotoxin Therapy

Spectral Diagnostics's Endotoxin Activity Assay will be used to measure endotoxin levels during the enrolment of patients in a Phase III sub study, part of a multinational clinical trial evaluating the safety and effectiveness of a treatment for severe sepsis.

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Knowing Doctor's Financial Interests Doesn't Deter Clinical Trial Participants

A patient's willingness to participate in a clinical trial may be unaffected by the disclosure of a researcher's financial interests in the study, unless the amount of money a researcher stands to earn depends on the results of the trial.

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Synosia Starts Phase II Efficacy Trial For Rufinamide

The trial is an eight-week, double-blind, placebo-controlled, exploratory study being conducted in 20 sites in the United States. It will assess the efficacy and tolerability of rufinamide in up to 230 patients with general anxiety disorder, as measured by multiple psychometric assessment tools. Patients randomized to rufinamide will receive 250mg twice a day for one week followed by 500mg twice a day for seven weeks. The trial design was guided by the encouraging results of a proof-of-concept study announced in January 2008.

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IntelliPharmaCeutics Completes Trial For Abuse, Alcohol Resistant Sustained Release Oxycodone

IntelliPharmaCeutics announces significant results from a recently completed pilot clinical trial for its new abuse-resistant, alcohol-resistant once-a-day oral oxycodone formulation by its operating company IntelliPharmaCeutics.

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Aeterna Zentaris Initiates Trial Of Cetrorelix For Benign Prostatic Hyperplasia

Aeterna Zentaris reported dosing has commenced with its flagship product candidate, cetrorelix in the second efficacy study of its Phase 3 program in benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate.

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Nventa Announces Positive Data From Cervical Dysplasia Trial

Nventa Biopharmaceuticals Corporation announced interim immunological data from the first two cohorts of its ongoing Phase 1 clinical trial of its lead product candidate, HspE7, in patients with cervical intraepithelial neoplasia, or CIN, a precursor to cervical cancer.

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Alexza Initiates AZ-007 Clinical Trial

Alexza Pharmaceuticals has initiated a Phase 1 clinical trial with AZ-007 (Staccato zaleplon). AZ-007 is an inhalation product candidate being developed for the treatment of insomnia patients who have difficulty falling asleep, including patients who awake in the middle of the night and have difficulty falling back asleep. This is the first clinical trial of AZ-007 being conducted under an IND filed

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Data Show Transfusion Patterns In Chemotherapy-Induced Anemia Patients

Analyses reported a significantly lower proportion of patients receiving transfusions when ESAs treatment was initiated at hemoglobin levels between 10 to 11 grams per deciliter of blood compared with patients having Hb levels less than 10 g/dL prior to ESA treatment.

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Kiadis Pharma Successfully Completes Rhitol Clinical Study

Kiadis Pharma has successfully finalized its Rhitol Phase II clinical trial with the last patient completing its six month treatment cycle. Rhitol is evaluated as treatment for patients with extensive chronic Graft versus Host Disease (GvHD) intolerant or resistant to standard immunosuppressive treatment.

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