Atomic Movement Study May Influence Design of Pharmaceuticals
The research, funded by the Engineering and Physical Sciences Research Council (EPSRC), will further understanding of how to control chemical reactions and will influence improvements in a range of important processes from the design of biopharmaceuticals to the engineering of new catalysts, enabling scientists, for example, to develop products in more environmentally friendly ways.
The Liverpool team created a porous crystal which has 'walls' of atoms and cavities which act as containers for molecules. They used this crystal to accommodate a set of molecules as they took part in a chemical reaction similar to reactions by enzymes and proteins to regulate and keep alive living systems.
The crystal was put into a powerful X-ray diffraction machine at Daresbury laboratory, Warrington.