Lacromin Provides Cost-Effective Improvement Over Transferrin

Armen Hareyan's picture


InVitria has released data that shows that Lacromin, a recombinant growth factor for cell culture media outperforms transferrin and provides a cost-effective solution to rising transferrin costs.

Because Lacromin is produced in a completely animal-free system, it provides improved productivity and safety over animal-derived alternatives including bovine and human transferrin. In addition data has shown that Lacromin significantly increased the productivity of antibody production when compared with these other sources of transferrin.

"We are excited about Lacromin and its success as safer, more productive replacement for transferrin," said Victor Hicks, Vice President and Commercial Director, InVitria. "Lacromin provides a cost-effective solution to the challenge of rising transferrin costs and increasing concern over the use of animal-derived ingredients in cell culture. Given the FDA's preference for non-animal derived cell culture media ingredients, animal-free recombinant proteins like Lacromin are a real breakthrough for this market."

InVitria markets Lacromin to customers that seek a serum-free and animal component free cell culture media source for their biopharmaceutical production.

About Lacromin

Lacromin is recombinant human lactoferrin derived from plants. Lacromin holds many advantages over current cell culture media ingredients:


-- Strong growth factor

Lacromin has been shown to promote cell growth in many cell lines, including Chinese Hamster Ovary (CHO) cells and Mouse Hybridoma cells.

-- Outperforms Transferrin

Lacromin promotes higher cell density and reduces cell doubling time when compared with Transferrin.

-- Replaces Animal Derived Transferrin

Since Lacromin is derived from plants, it is free of any viral or prion contaminant risks.

-- Improves IgG Productivity

In Hybridoma cells, Lacromin increased IgG productivity by 50% versus Transferrin and by 6% versus Fetal Bovine Serum (FBS).