New gene risk factor as cause of Alzheimer's disease
Cause of Alzheimer's Disease
Variations in a gene known as SORL1 may be a factor in the development of late onset Alzheimer's disease, an international team of researchers has discovered. The genetic clue, which could lead to a better understanding of one cause of Alzheimer's disease, is reported in Nature Genetics online, Jan. 14, 2007, and was supported in part by the National Institutes of Health (NIH).
The researchers suggest that faulty versions of the SORL1 gene contribute to formation of amyloid plaques, a hallmark sign of Alzheimer's disease