New Anti-wrinkle Cream Can Double Face's Ability To Repair Itself
A news release from the University of Reading announces that Reading scientists have discovered that an anti-wrinkle chemical used in some anti-wrinkle creams really does work in tightening human skin - so much so, that in a high enough dose it can nearly double the amount of collagen in your skin.
The results of this study are published in the current issue of the scientific journal Molecular Pharmaceutics, where scientists test the anti-wrinkle chemical ingredient Matryxl™.
What makes Matryxl™ especial is that it consists in part of a peptide amphiphile called “Peptide Amphiphile C16–KTTKS” that has generated the interest of scientists working in tissue engineering who have believe that Peptide Amphiphile C16–KTTKS has promising abilities for wound healing in battlefield applications for soldiers.
Peptide amphiphiles are an extraordinary class of molecules that have the built-in ability to act as bioactive materials that can self-assemble into a variety of nanostructures - such as fibers with a cylindrical geometry that can become part of normal native tissue. Scientists involved in these self-assembling molecules are investigating ways to interface these materials with biology, specifically for treating spinal cord injury, inducing angiogenesis, constructing materials for hard tissue regeneration and replacement, and cosmetics where collagen is an important part of connective tissues like skin and is involved in wound repair.
"Collagen-based materials have immense potential in tissue engineering," says co-author Professor Ian Hamley.
Although scientists within the cosmetic industry have known about the effectiveness of collagen-promoting chemicals like those found in Matryxl™, their research typically is not published or shared at scientific meetings due to proprietary interests in preventing competitors from discovering their secret formulas in skin care products. Therefore, consumers typically do not hear about the research that can back up what appears to be nothing more than marketing hype about how great and effective a product is.
In the study published in Molecular Pharmaceutics, the researchers applied the active ingredient of Matryxl™ to human skin cells as well as corneal fibroblasts (eye tissue) and found that in high enough doses that the Peptide Amphiphile C16–KTTKS component of Matryxl™ stimulated collagen production in a dose-dependent manner.
The authors of the paper conclude that Peptide Amphiphile C16–KTTKS results in self-assembly and stimulation of collagen in skin, demonstrating that this chemical used in some anti-wrinkle creams is effective and can enhance skin elasticity and be used to remove wrinkles in anti-wrinkle cream products.
For additional information on removing wrinkles, follow the links to the articles listed below:
Image Source: Courtesy of MorgueFile
Reference: “Collagen Stimulating Effect of Peptide Amphiphile C16–KTTKS on Human Fibroblasts” Molecular Pharmaceutics, 2013, 10 (3), pp. 1063–1069; Roanne R. Jones et al