Insights Could Yield New Approaches to Nerve Regeneration.
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Brain & Nervous System
This may provide novel therapeutic targets for curing PMDD or other mental or neurological disorders related to changes in steroid hormone levels.
IARC scientists establish abnormal DNA damage response as the cause of neuronal defects in chromosome instability and tumor-prone disorders.
Different strokes: Differences in symptoms may help explain variation in treatment and effects. Strokes are "brain attacks," they starve part of the brain of oxygen.
New research shows that farmers who used agricultural insecticides experienced increased neurological symptoms, even when they were no longer using the products.
Variation in the relative harmoniousness, or "consonance," of different tone combinations arises from people's exposure to the acoustical characteristics of speech sounds.
Besides providing a better understanding of brain rewiring, the researchers believe the findings might yield insights into such disorders as epilepsy and Alzheimer's disease.
The brain is the most complex structure in the known universe. SPECT, which is an acronym for Single Photon Emission Computerized Tomography, is a sophisticated nuclear medicine study that examines blood flow in the brain.
The classification scheme may provide important preoperative guidance to neurosurgeons, increasing the chances of preserving the patient's life.
Researchers have identified the second of three genes that can each independently cause the disorder known as cerebral cavernous malformations.
Patients often undergo a lengthy process of trial and error to find the dose of anti epilepsy drugs appropriate for them.
Research has linked a gene previously shown to play a role in learning and memory to the early manifestations of drug addiction in the brain.
The research team is now working to develop prototype devices that may enable paralyzed people to operate "neuroprosthetic" and other external devices using only their brain signals.
A major form of one of the most prevalent inherited neurological disorders in humans, Charcot Marie Tooth disease (CMT), stems from an abnormality in the cellular powerhouses, or mitochondria, that fuel the nerves required for muscle control.
Without even a scar on her scalp, Paula Alters had major brain surgery. That is to say, a tumor was removed from her brain and a knife never came close to her head.
Researchers report that people with key variations in a gene that affects the ability of blood vessels to relax are 10 times more likely to suffer a stroke from a ruptured brain aneurysm than people who have aneurysms but lack these key genetic variations.
Neurobiologists have found that switching off a single gene for a neuronal protein prevents epilepsy in a mouse model of human epilepsy. They said their research offers the hope of drugs that could prevent the alterations in the brain that cause the normal brain to become epileptic.
Serotonin is a "neurotransmitter," a chemical that one neuron uses to trigger a nerve impulse in its neighbors. Thus, serotonin levels can profoundly affect brain function, and therefore behavior.
Infinitesimal particles of gold have enabled neurobiologists to track down key molecules in the machinery of "entry points" in neurons, offering clues to the organization of a region that has thus far remained largely unknown neuronal territory.
The Duke study is the first to identify where the cln3 protein resides in human brain cells and to link the protein's location to its function. The researchers discovered that cln3 transports a vital lipid, or complex fat molecule, within a cell.
Neurobiologists have pinpointed the molecular storehouse that supplies the neurotransmitter receptor proteins used for learning related changes in the brain.
Researchers have found a slightly elevated risk of "ischemic" stroke due to a blood clot in the brain in patients treated with tamoxifen.
Neurobiologists believe that their new analytical technique will enable unprecedented insights into function of both the healthy brain and those afflicted with neurological disease.
The protein is known as mBDNF, which stands for mature brain-derived neurotrophic factor. mBDNF is essential for the formation of long-term memory, the ability to remember things for longer than a day.