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Vitamin C Worsens Knee Osteoarthritis in Animal Study

Armen Hareyan's picture

DURHAM, N.C. - High doses of vitamin C increase the severity of spontaneous knee osteoarthritis in an animal model of the disease, according to a new study by Duke University Medical Center researchers.

The results contradict previous short-term studies in guinea pigs and an epidemiologic study in humans that suggested vitamin C might protect against osteoarthritis, said lead investigator Virginia Kraus, M.D., associate professor of medicine at Duke University Medical Center. The study was published in the June 2004 issue of Arthritis