Very Early Signs of Atherosclerosis and Heart Failure Seen Together on MRI
Subtle changes in heart function
Middle-age and older people who feel healthy, but who have early signs of atherosclerosis, are more likely to exhibit subtle changes in heart function, detectable through a special MRI technique, which may signal the beginning of heart failure, according to a new study in the June 20, 2006, issue of the Journal of the American College of Cardiology.
"The novelty of this study is that we were taught that the way atherosclerosis causes myocardial dysfunction is by causing heart attacks or chest pain or other clinical manifestations of disease. Here we have evidence that subclinical atherosclerosis, atherosclerosis that has not manifested clinically, is influencing left ventricular function, regional myocardial function, before any clinical outcome is detected. This is a paradigm shift in the way we understand how myocardial dysfunction is produced. And that speaks to the importance of the report," said Jo