Naltrexone May Increase The Urge To Drink

Armen Hareyan's picture

Naltrexone Alcohol Treatment

Naltrexone (NTX) is an opioid antagonist medication used for the treatment of alcoholism.


NTX may be more effective among individuals with a family history of alcoholism, suggesting a genetic influence on treatment response.

Findings indicate that Asp carriers of the OPRM1 gene who take NTX have a greater urge to drink, which is contrary to expectations.

Naltrexone (NTX) is able to reduce drinking and craving among many alcoholics and heavy drinkers, but not all of them. Polymorphisms in the D4 dopamine receptor (DRD4) gene and the