HIV in late childhood and adolescence a growing problem
Scientists have highlighted for the first time the plight of the growing number of older children and adolescents living with undiagnosed HIV and AIDS in Africa. In a study published today in Clinical Infectious Diseases, Wellcome Trust researchers claim that delay in recognising this problem means that the needs of this important group are not being met.
It is estimated that half a million babies were infected with HIV during birth or breastfeeding in 2006, passed down from their mothers. It was assumed that their chances of survival to adulthood were negligible. However, a new study, carried out by researchers based at the Connaught Clinic in Harare, Zimbabwe, shows that older children and adolescent with AIDS have all of the features that would be expected from long-term survivors of infant HIV infection.
"The findings are quite extraordinary," says Dr Liz Corbett, a Wellcome Trust Senior Clinical Fellow in Tropical Medicine from the London School of Hygiene and Tropical Medicine, based in Zimbabwe. "The phenomenon of long-term survival is poorly recognised and until recently has been almost positively resisted by the international HIV community because of the strongly held assumptions that HIV in late childhood is very unusual, and that survival from birth to adolescence with HIV was so unlikely without treatment as to be negligible. This just doesn