Uterine Cancer May Be Clue To Inherited Syndrome
Cancer and Inherited Syndrome
A new study suggests that women with endometrial cancer should be screened for inherited mutations that could lead to a high risk of several other cancers.
The study showed that 1.8 percent, or about one in 50, of newly diagnosed endometrial cancer patients have mutations for Lynch syndrome, an inherited condition also known as hereditary nonpolyposis colon cancer, or HNPCC.
People with Lynch syndrome mutations are at high risk for colon, endometrial, ovarian and gastric cancer. Endometrial, or uterine, cancer is the most common cancer in women with this condition.
The study, led by researchers at The Ohio State University Comprehensive Cancer Center