Egg's Energy Stores Key To Preserving Fertility

Armen Hareyan's picture

Infertility and Women's Health

An immature egg's internal nutrient supply is critical to its survival, an insight that offers a new route to understanding and treating infertility due to egg death, according to Duke University Medical Center researchers.

As women age, their stockpile of immature eggs, called oocytes, diminishes through cell death, eventually leading to infertility. In studies with frog oocytes, the Duke researchers found that the nutrient storehouse, or yolk, plays a key role in regulating the survival of these cells. Depleting the nutrients triggers apoptosis