Abnormal Immune Cells May Cause Unprovoked Anaphylaxis

Armen Hareyan's picture



Two new clinical reports shed light on why some people suffer from recurrent episodes of idiopathic anaphylaxis - a potentially life-threatening condition of unknown cause characterized by a drop in blood pressure, fainting episodes, difficulty in breathing, and wheezing.

In some of these individuals, researchers have found mast cells (a type of immune cell involved in allergic reactions) that have a mutated cell surface receptor that disturbs normal processes within the cell.

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