Ovarian cancer is the most lethal of all gynecological malignancies. This is in part because of the symptomology of the disease until it is at a late stage. Because of the five-year survival rate is only 45% while the actual cause of epithelial cancer of the ovary or fallopian tube is not known, studies have found about 15% are shown to be connected with the inherited genetic factors such as BRCA 1&2 mutations. The standard line of defense is surgery and treatment with platinum-based chemotherapy. Unfortunately, recurrence is high with the recurring disease resistant to further chemotherapy. Recently olaparib has shown some promise in treating BRCA 1&2 mutations that have led to ovarian cancer. It is thought this occurs along the DNA repair pathways that make the cancer cells sensitive to olaparib. The validity of the study's data was confirmed by repeated tests across different fields (Fleury et al. 2017).

Financial concerns are often cited by doctors as a barrier to administering routinely recommended vaccines to adults. Survey respondents answered questions on payment and profit for various public and private payer types. Over half of respondents reported losing money vaccinating adult Medicaid beneficiaries. Few respondents reported negotiation with manufacturers or insurance plans on vaccine purchase prices or payments for vaccinations. Claim denial is a major reason many adults don't inquire about vaccinations or seek them out with their doctors (Lindley et al, 2018; Potter et al, 2018).

Prescription drug monitoring programs are central to federal and state policy responses to address prescription abuse. They are state run electronic database s of prescription medications. Unfortunately, even with these programs in place, there is evidence of limited benefit. Finds of the study suggest drug monitoring programs have a limited impact on individual level opioid utilization. They agree that further studies are needed (Moyo, 2017).

It has been reported by the GAO-government accountability office, that prices on drugs doubled between 2000 and 2008. The rise was attributed to industry consolidations and price hikes by third-party providers who repackage drugs. And while generics can lower the prices after branded patents expire, branded manufacturers lose approximately 80% of their market share. It should also be noted, that in the US it takes an average of 12 years for a drug to pass through all the trials as it moves from test tube to patent. And the patent protection starts when the molecule is first registered with the patent office. So once it is released for sale the companies often only have 8 years on average to recover the costs of research and productions of the medication and turn a profit (Dooney & Hunter, 2014).

Technological advances have increased tremendously our understanding of molecular characteristics and genetic drivers for a variety of brain tumors. Although targeted therapies have had a considerable impact on patients outcomes, GBM remains an exception. the identification of targetable driven mutations in GBM has opened new potential treatment options for affected patients. On the basis of these findings, the efficacy of new targeted agents is currently being investigated in clinical trials (Ippen et al, 2018).

Healthcare-associated infections (HAI) can be reduced by up to 55% by systematically implementing evidence-based infection prevention and control strategies. HAI come at a considerable expense to patient and families but also cost the US healthcare system an estimated $9.8 billion each year. This study found healthcare institutions have a responsibility to improve the quality of patient care and reduced infection rates by effectively implementing customized multifaceted strategies and improved patient outcomes (Schreiber et al, 2018).

As more Americans age, there is an increasing number of older adults who are still not able to access the care they need for an acceptable quality of life.

Ever since the implementation of electronic health records and the restraints of the Affordable Care Act, doctors have been leaving the workforce in increasing numbers. Many doctors have said it is because of with the electronic records they are always waiting for someone to put the information in the system, creating sometimes life-threatening delays in care. In addition, there has been a decrease in the numbers of young adults entering medical schools. This combination creates the shortage of manpower and the greater chance of burnout.

Recently, WHO (World Health Organization) recommended the use of rotavirus vaccinations worldwide. The widespread use of these vaccines has the potential to prevent about two million deaths over the next decade. Even countries like Mexico are suggesting the use of rotavirus vaccine to have a substantial reduction of mortality of those affected.

Testing by using already approved medications are being used to aid in treatments for fatal diseases like HIV-1 and Ebola

Parkinson’s disease does not seem as important as curing cancer or studying stem cells uses. However, as prevalence grows, perhaps, the money to research will follow. A very large sampling is projecting double the cases of Parkinson's Disease by 2030. It will be interesting to see if projections are accurate considering very little is known about the cause, and much less how to treat successfully.

Jennifer Jones looks incredulously around her. She does understand what is going on; she seems to be in a trance. Lying on a bed at the Mayo Clinic in Rochester, Minnesota, surrounded by machines that keep her balanced and with wires going in and out of her body, she will experience something new. And she is nervous. For the first time, she can breathe on her own after a lung transplant surgery.

Social insects like bees and ants can help us develop new drugs against antibiotic-resistant bacteria. This is due to the fact that they have developed alternative strategies to defend themselves against the higher exposure to pathogens associated with social life.

Experts share flu season is likely to be severe, making it important to get your flu shot, especially for those age 65 and above. EmaxHealth asked Dr. Adam Welch, Associate Professor at the Bill Gatton College of Pharmacy at East Tennessee State University and Gina Venditti MPAS, PA-C, Board of Trustees, Physician Assistant (PA) Foundation why it is so important for older adults to get an annual flu vaccine.

Anyone with a disability has likely suffered through questions that are - so to speak - truly insufferable. Some people are upfront about their disability and willing to share; while others may not have any visible signs. One should never assume. Here is a list of seven stupid and inappropriate things that people with disabilities have been asked.