Common PTSD Drug Is No More Effective Than Placebo

Armen Hareyan's picture
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Guanfacine, a medication commonly prescribed to alleviate symptoms of post-traumatic stress disorder, is no more effective than a placebo, according to a study led by researchers at the San Francisco VA Medical Center.

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"There was no benefit at all, and there were several adverse side effects," says lead author Thomas Neylan, MD, medical director of the PTSD treatment program at SFVAMC. "People with symptoms of PTSD should probably stay away from this drug and others of its type."

The study appears in the December 1, 2006 issue of the American Journal of Psychiatry.

Guanfacine belongs to a class of medications known as alpha-2 agonists, which lower the brain

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