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Depression Symptoms Treatment

It's time to relegate prescription medications for anxiety and depression to last resort treatment

Depression and anxiety

I recently wrote a book on treating anxiety disorders, Anxiety Protocol, and asked a psychiatrist colleague to review the book. He stated he liked the book very much, and was in full agreement with the recommendation of cognitive behavioral therapy (CBT) as first-line treatment for anxiety disorders. However, he disagreed initially with my recommendation that prescription medication for anxiety disorder should be last resort treatment, and only then should be prescribed for severe cases or for psychotherapy-resistant cases. My colleague went on to opine that in moderate to severe cases, he saw the use of prescription medication “in association” with CBT, or as an adjunct to CBT, not as a “last resort.” Otherwise, he found contents of the book very useful.

Managing Cognitive Disturbances in Major Depression: An Unmet Need

Major depression

Major depression is characterized by mood symptoms, disturbances in sleep, appetite, energy, psychomotor function and suicidality. Cognitive disturbances like problems with learning and episodic memory while an integral part of major depression have been relatively neglected until recently primarily because the available treatments have shown little efficacy in improving these symptoms. Only 35% of patients with MDD achieved remission on monotherapy with citalopram in the STAR-D trial and even after four levels of treatment almost 40% of patients had not achieved remission. Moreover the rates of relapse and recurrence were extremely high over a one year follow up period even in those who achieved remission.

Depression linked to celiac disease

depression and Celiac Disease

Several studies have found a connection between depression and celiac disease, but a clear cause and effect relationship has not been established. Some people who have this disorder also experience the symptoms of depression, and research indicates it is worse in untreated celiac cases. However, a wide range of experiences have been recorded that indicate treating celiac disease does not automatically eliminate depression.

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