Researchers Find Gene Determinants Of C-Reactive Protein

Armen Hareyan's picture

Researchers at Brigham and Women's Hospital (BWH) have found that variation in several genes that are associated with metabolic and inflammatory regulation - in diseases such as diabetes and heart disease - also have significant effects on C-reactive protein (CRP) levels.

CRP is a marker of inflammation in the bloodstream, measured by a simple blood test that has been shown to predict heart attack, stroke, and cardiovascular death, even among individuals with low levels of cholesterol. Lifestyle modifications, such as weight loss and regular exercise, has been shown to lower CRP levels, but there has also been concern

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