New Review Adds More Reasons To Avoid Diabetes Drug Avandia

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Avoid Diabetes Drug Avandia

Little evidence supports using rosiglitazone (Avandia) to improve the quality or length of life among adults with diabetes.

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Furthermore, data suggest that the drug might worsen complications of the disease such as weight gain, swelling, bone fractures and heart disease. The new review supports findings from an analysis of studies, published in May, which reported an increased risk of death from cardiovascular causes in patients taking the medication.

On May 21, the Food and Drug Administration issued a safety alert saying, "Patients who are taking Avandia, especially those who are known to have underlying heart disease or who are at high risk of heart attack, should talk to their doctor about this new information."

"The benefit-risk ratio of rosiglitazone therapy in type 2 diabetes mellitus needs urgent clarification," say the authors of the latest review, led by Bernd Richter, M.D., of Heinrich-Heine University. "New safety data

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