No Proven Role For Diet In Treating Rheumatoid Arthritis

Ruzanna Harutyunyan's picture

A new review finds no definitive connection between diet and rheumatoid arthritis (RA), a disease in which the body’s immune system attacks the lining of the joints.

As an individual’s rheumatoid arthritis progresses, his or her joints can become swollen and stiff, reducing mobility. While treatments are available to relieve some of these symptoms, no cure exists.

Although sufferers of rheumatoid arthritis have turned to a variety of special diets, the new review of 15 studies found little evidence that changing their diets made any significant difference.

“There are different theories behind certain diets,” said Kare Hagen, the lead review author. “There are some reports showing that food allergy or intolerance is present or even common in RA patents.” However, she said, “No body of evidence exists for dietary intervention for RA.”

Hagen is a senior researcher at the National Resource Center for Rehabilitation in Rheumatology of the Diakonhjemmet Hospital in Oslo, Norway.

The new review appears in the latest issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews like this one draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

Of the review studies, one found that fasting followed by 13 months on a vegetarian diet might reduce pain by 1.89 percent on a scale of zero to 10, but had no effect on physical function or morning stiffness.


In another study, a 12-week Mediterranean diet reduced pain by 14 percent, but had no effect on physical function or morning stiffness. The Mediterranean diet is high in fruit, vegetables, cereals and legumes, fish and olive oil, and low in red meat.

Two studies looked at the use of an elemental diet, consisting of hypoallergenic, easy-to-digest food. The diet, sometimes prescribed for patients with Crohn’s disease, made no significant differences in pain, function or stiffness in participants with rheumatoid arthritis. Studies on vegan diets and elimination diets, which remove one or more food items from the diet to see if improvement occurs, were inconclusive.

Overall, study participants who were placed on a diet were twice as likely to drop out as those in control groups were. Those who did change their diet lost more weight, up to six and a half pounds, without intending to do so — not necessarily a good thing for these people.

Reviewers explained that some of the diets, without special planning, could cause a deficiency in important vitamins and minerals. People with rheumatoid arthritis might already find it difficult to buy and prepare food, so a special diet could put them at a further disadvantage.

“Considering that many RA patients are already at nutritional risk, we cannot consider weight loss as a solely beneficial effect,” Hagen said.

“As the authors conclude, there is not enough information to make a strong, scientifically based recommendation regarding use of dietary changes to control RA inflammation symptoms,” said Mark Wenner, M.D., a professor at the University of Washington School of Medicine. “One of the problems is that there are few well-done clinical studies that have investigated the influence of diet on RA inflammation and the studies that have been done differ from one another.”

Still, diet does offer other benefits for related conditions for which RA patients are at increased risk, Wenner said. “For example, attention to dietary and nutritional factors that lower risk for cardiovascular disease and osteoporosis is particularly valuable for RA patients.”

For Wenner, the review confirmed the benefits of the Mediterranean diet, which he recommends as a healthy heart diet. While the improvement in rheumatoid arthritis generally is modest, he said, the Mediterranean diet poses little risk.



We all know that > traditional FOOD Allergy Testing ( as probably reflected in the ABOVE Research #'s ) is done via Skin / IgE Testing.... and will surface Immediate FOOD Allergy Sources. Immediate = Eat a Peanut = Trouble. Perhaps if they Measure .. and then look at Delayed IgG & IgG4 FOOD Allergy Data / Presence ..gathered via a standard BLOOD Test... It may surface a relationship between Delayed FOOD Allergy Sources and RA. It is Important to Test / Treat BOTH Sides of the allergy COIN > Enviro & FOOD ( Immediate & Delayed ) to fully address / Neutralize a Patient's Allergy Profile. Regards. Stephen Principal of an Allergy Services Company supporting Physicians with: Enviro & FOOD ( Both IgE Immediate & IgG Delayed ) Allergy Testing, enviro ImmunoTherapy Vaccine & Custom FOD Allergy DIET Plans... Got ALLERGIES ? WHY ? >>
Given all the other health benefits of the Mediterranean diets, pain reduction is icing on the cake. Steve Parker, M.D.
I have been on a vegetarian (vegan -no dairy) diet for 4 months because I was diagnosed 4 months ago with RA. I also started methotrexate 2 months ago. I feel better overall due to being on a vegan diet. my hair is shinier. My skin is healthier no breakouts. I don't feel lethargic like I use to. I did lose weight 5 pounds because I no longer eat fried foods which I think is really good! I went from a size 8 to a size 6 ajnd I look really hot for being 49! Looking back I realize that I was eating alot of foods that are not good for me and I was a junk food junkie and diet coke aholic. I realize that I probably set the stage for my body to say enough is enough. I wish that I had eaten better all along and I could have possibly avoided some fo the pain and suffering. I won't go back to my old lifestyle because I can see a difference. My RA is still there but I feel that I'm taking care of my body and doing my part to keep my body fine tuned and healthy so that it can withstand the drug therapy. I think there are many benefits to eating healthy that help us in the long run. I am going to add more of the mediterranean suggestions because a 14% reduction in pain is awesome which may result in reducing meds. Rita
how long did they fast for? the study was only done on 15 people?! i agree about the blood have to find delayed reactions, that's how i got rid of my ra. This study sounds like b.s. Also, only a VEGAN diet will really help. And, the problem is, every person with RA has slight variations in what their body will tolerate. You can't do the same test on everyone or only one test on everyone. You won't get any results that way.
I have to agree with most of what has been said above. Any pain reduction is a plus. Yes, it's harder to prepare food - I can't do it all the time - but when I do I feel - a) I enjoy doing it! I'm not above getting the $12 PRoctor-Silex food chopper or the can-opener for when I can't do those things, or jar opener.... it's worth it! So I'm b) more independent, c) I can prepare what's best for me (my husband is a great cook, and does what he can - but this way he can be freed up to cook as much meat or past as he wants without feeling like he always has to cook veggies & fish for me!) I have been vegetarian and I have been meat-eating. Sometimes I feel like I need the extra protein, but normally, when I manage to stay my chosen "semi-vegetarian=veggies plus fish" self, that's the best. And not too much fish, please - my system has trouble with all that protein, as good as it is! The better food you eat, the less junk you will eat, the better you will feel, the more you can do, the more exercise - and that is major. Ellen