New Study Reveals Artificial Sweeteners Linked to Increased Obesity, Diabetes

Artificial Sweetener linked to Obesity

The study was published Monday in the Canadian Medical Association Journal, and compared and compiled the results of 37 previous studies. Seven of these studies were shorter-term randomized trials that included about 1,000 participants, and the remaining 30 were observational studies that tracked the health and lifestyle habits of approximately 406,000 people over time.
Researchers determined that people who regularly consume zero calorie sweeteners--including the most popular, Saccharin, Aspertame, Sucralose—actually had more instance of weight gain, obesity, and diabetes. These results may be surprising to many who assume that the consumption of artificial sweeteners is a healthy alternative to consumption of sugar.

“I think there’s an assumption that when there are zero calories, there is zero harm,” says Meghan Azad, PhD, author of the study and research scientist from the University of Manitoba. "We were really interested in the everyday person who is consuming these products not to lose weight, but because they think it's the healthier choice, for many years on end.”

While the study suggests that more research needs to be done to determine the potential long-term effects of artificial sweetener consumption, from what we know now, "there is no clear benefit for weight loss, and there's a potential association with increased weight gain, diabetes and other negative cardiovascular outcomes," says Azad.

According to Azad, over 40% of adult Americans consume zero-calorie artificial sweeteners on a daily basis. They are seemingly Omni-present, and in sources many people would never suspect, from chewing gum to salad dressings and yogurt. Studies that measure the sweeteners in blood and urine have shown that many people who report not using artificial sweeteners are unknowingly consuming them.

The not-so-sweet side of artificial sweeteners

There are just five artificial sweeteners approved by the Food and Drug Administration for use in the United States: acesulfame potassium (sold as Sunett and Sweet One), aspartame (sold as Equal, Nutrasweet and Sugar Twin), neotame (sold as Newtame), saccharin (sold as Sweet'N Low, Sweet Twin and Necta Sweet) and sucralose (sold as Splenda). One more, cyclamate, is widely used in more than 100 countries, but banned in the United States.
The FDA says all five approved sweeteners are safe as long as they are used in moderation. That means no more than 23 packets a day of Splenda, Sweet One or Newtame, 45 packets a day of Sweet'N Low, or 75 packets a day of Equal.

Unfortunately, the evidence keeps mounting that even very moderate use of artificial sweeteners can have serious health effects. There are a bunch of hypotheses for why artificial sweeteners may cause weight gain or be in other ways detrimental to our health. They may sharpen a sweet tooth, for example, prompting you to eat more sugary foods, or they may make you feel virtuous but then overcompensate later. Or the sweet taste paired with no calories may confuse the body and change how it handles real sugar, as has been shown in lab animals. Sweeteners may also alter the microbiome in ways that change metabolism for the worse.

"Based on all of the research done so far, there is no clear evidence for a benefit, but there is evidence of potential harm from the long term consumption of artificial sweeteners," said Azad. "This should inspire consumers to think about whether they want to be consuming artificial sweeteners, especially on a regular basis, because we do not know if they are a truly harmless alternative to sugar."

What’s so bad about sugar?