Moringa Oleifera plant is anti- diabetic and anti- obesity, according to multiple animal studies
This one plant called Moringa Oleifera plant, also known, as drumstick tree or horseradish tree has been scientifically proven to have anti-diabetic and anti-obesity capabilities. Keep reading to know more about what scientists observed!
Here is what Moringa Oleifera was observed to do inside the body of mice, warranting its label of anti- diabetic and anti- obesity plant
In order to explain the molecular mechanisms of the potent anti-obesity effect of Moringa oleifera, scientists administered 600 mg/kg of the ethanolic stract made from the plant for a period of 12 weeks. It was observed that Moringa Oleifera plant acts directly on the adipokines of the visceral adipose tissue, which mediate inflammation and insulin resistance. Moringa’s extract also down-regulated mRNA expression of leptin and resistin, while it up-regulated adiponectin gene expression in obese rats relative to untreated obese control counterparts. This amelioration of genes expression was paralleled by a reduction in body weight.
In an animal model study, a leaf protein isolate was obtained from Moringa oleifera leaves, named Mo-LPI, and the hypoglycemic and antioxidant effects on alloxan-induced diabetic mice were assessed. Scientists observed that a single-dose intraperitoneal administration of Mo-LPI (500 mg/kg·bw) reduced the blood glucose level (reductions of 34.3%, 60.9% and 66.4% after 1, 3 and 5 h, respectively), but it also was also effective in reducing the oxidative stress in diabetic mice by a increase the activity of catalase, a very important enzyme in protecting the cell from oxidative damage. Moraga's extract also decreased the levels of malondialdehyde coumpound, which is a marker of oxidative stress, a process that may lead to chronic inflammation.
Moringa Diabetes Research
In yet another animal model of Moringa diabetes research, scientists admnistered a lower concentration of Moringa Oleifera’s methanolic extract (250 mg/kg) on diabetic rats for 42 days. Moringa Oleifera’s methanolic extract was shown to have hepatoprotective, anti-inflammatory, and lipid-lowering effects against streptozotocin-induced hepatotoxicity.
Interpreting these findings, other health benefits of Moringa Oleifera and more
We can only appreciate how important these findings really are, when we understand what each mRNA expression means in terms of how that helps an individual to reset his/her body’s metabolism either to loose weight, counteract diabetes or both. For example: While the regulation of Leptin is paramount for weight loss because leptin is your “hunger hormone,” and its regulation means that your appetite will decrease; The regulation of Resistin is equally important, because Resistin is an adipocyte-specific hormone that links obesity to type 2 diabetes.
Another important finding in these studies is that moringa’s oleifera hepatoprotective activities are specially of great benefit for those fighting diabetes, because it is well know that diabetics are more likely to develop liver disease.
According to Overweight & Obesity Statistics, only in the US, 2 in 3 adults are considered to be overweight or obese. The CDC estimates that 29.1 million people of the American population have diabetes. Therefore, it is important to start clinical trials in humans on whether the same effects are observable in humans. If proven as effective in maintaing its anti - diabetic and anti - obesity capabilities, moringa Oleifera will revolutionize treatment for both diseases, since it comes from nature and is a relatively cheap supplement.
Being anti- diabetic and anti- obesity are not the only “superpowers” of Moringa Oleifera, as this plant has been reported to help improve cognition in people with alzheimer’s disease, and be a potential treatment for cancer.