Ketogenic diet is an effective treatment for cancer patients, confirm studies
Ketogenic diet (KD), which is a high-fat, adequate-protein, low-carbohydrate diet has been used for decades by cancer patients, and there are countless anecdotal evidence that suggests its effectiveness. Recently, studies have revealed that Ketogenic diet is an effective treatment for cancer patients. He is what some studies revealed about the safety and efficacy of going on a ketogenic diet if you have been diagnosed with cancer.
A study on the safety and tumor inhibitory effect of ketogenic diet for pediatric patients with malignant brain tumors, has found that KD was not only safe but also provided good quality of life.
In a 8 week study, on two pediatric oncology patients with astrocytoma tumors ( brain cancer), found that within 7 days of initiating a ketogenic diet, blood glucose levels declined to normal levels, and blood ketones were elevated 20 to 30 fold. Results of pet scans revealed that, there was a 21.8% average decrease in glucose uptake at the tumor site in both subjects.
An in vivo, animal model, experiment to find out if a ketogenic diet is an effective treatment on malignant brain cancer, found that a ketogenic diet has anti-tumor and anti-angiogenic effects in experimental mouse, and human brain tumors when administered in restricted amounts. KetoCal (a nutritionally complete food designed to simplify and optimize the ketogenic diet ) was administered in restricted amounts, and was observed to significantly decrease the intracerebral growth of the tumors by about 65% and 35%, respectively. It also significantly enhanced health and survival relative to that of the control groups receiving the standard low fat/high carbohydrate diet.
Here is how a ketogenic diet is an effective treatment for cancer patients
The two scientifically observed ways in which a ketogenic diet is an effective treatment for cancer are: 1) KD affects glucose levels 2) KD increase cancer cell oxidative stress
1) KD affects glucose levels
One of the ways in which a ketogenic diet is an effective treatment for cancer, is because it affects glucose levels in the blood stream. In contrast to normal cells, cancer cells demonstrate increased glucose consumption, even in the presence of oxygen, which was suggested to occur because of defective mitochondrial respiration requiring increased glycolysis as a compensatory response. But, numerous animal studies have not only confirmed the observation of increased glucose consumption in cancer cells but also demonstrate the importance of glucose for tumor survival and metastasis. The flux of energy-yielding substrates across colon carcinomas in patients has demonstrated that net glucose uptake and lactate release by malignant tumors exceeds the peripheral non-malignant exchange rates by 30 and 43 fold, respectively, while no significant differences existed between tumor and peripheral tissue in fatty acid or ketone balance.
2) KD increases cancer cell oxidative stress
The break down or storage of fats for energy, which are obtained from consuming food and absorbing them is called: Lipid metabolism. A ketogenic diet will affect the lipid metabolism by limiting the availability of glucose for glycolysis as mentioned above. This restricts the formation of pyruvate (made from glucose through glycolysis) and glucose-6 phosphate which can enter the pentose phosphate pathway forming NADPH necessary for reducing hydroperoxides, which in their turn have been observed to have a role in the pathology of cancer. When glucose metabolism is restricted in the case of feeding ketogenic diets, cancer cells will selectively experience oxidative stress.
It is important to note that if you have been diagnosed with cancer, chances are that what you are going to do from now on will impact your quality of life and even your possible complete healing. So, to change your lifestyle via dietary appropriate changes will impact the final outcome. Slowly, cancer patients are realizing that nutritional care is paramount in the road of cancer recovery, a 2017 german study revealed that Nutrition is an essential element in cancer care and that more people are interested in understanding the impacts of what they eat on the development or cure of their cancer- related illness.