Controlling Yeast infection can be a treatment for autism
The debate on what causes autism continues, but recent findings have confirmed that there is a gut brain connection that is disrupted in autistic people, and it is been discovered to be caused by an aggressive form of candida. This yeast infection causes havoc in the system, leading neurological issues, which are later labelled as autism. Therefore, controlling yeast infection can be a treatment for autism, and there is a case study to prove it.
Researchers from the Department of Experimental Medicine SUN-Second University in Italy, have conducted an experiment in which autistic patients stool samples were cultured. This simple experiment confirmed the theory that autistic patients have a deregulated gut functioning, which causes neurological issues, because the gut microbiota can modulate brain function. In this study, scientists found that in over half of the subjects, there was present an aggressive form of candida that causes yeast infection.
But, 5 more specific things were uncovered in this study: 1) Most dysbiosis (microbial imbalance) appears sustained by lowered Lactobacillusspp. and decreased number of Clostridium spp. 2) Absence of C. difficilis and its toxins in ASDs 3) Low-mild gut inflammation and augmented intestinal permeability were demonstrated together with the presence of GI symptoms 4) Significant linear correlation was found between disease severity and calprotectin and Clostridiumspp. Presence 5) Gastro Intestinal symptoms, such as constipation and alternating bowel, did correlate (multivariate analyses) with the increased permeability to lactulose.
Bellow, the implications of these fidings are addressed in terms of what they mean mean for the body, and how controlling yeast infection can be a treatment for autism
The human gastrointestinal tract is an ecosystem rich in microbial species where the Clostridium genus plays an important role. There are more than 200 known Clostridium spp. at least 30 are associated with human disease. This bacteria is well known as a gut colonizer, which is found significantly in infants and adults.
Lactobacillus spp. are important in human health, because they are part of the gastrointestinal endogenous flora and as a regulator of the vaginal ecosystem in women in their reproductive age. However, they are known also as pathogens, responsible for the septicaemia in immunocompromised patient, in cytolytic vaginosis and in lactobacillus's.
C. difficile bacteria is different in different age groups; it is highest in infants and decreases with age. During infancy, asymptomatic carriage of C. difficile in the gastrointestinal tract is very common. Many infants are colonized by C. difficile strains during the first 2 years of life but this colonization is rarely associated with C. difficile infection.
Calprotectin and Clostridiumspp presence
In the study at the Italian University, scientists found a significant linear correlation found between disease severity and calprotectin and Clostridiumspp. presence. This is a very consistent finding that confirm other studies, which have discovered that fecal calprotectin levels directly reflects the intestinal inflammation status of a patient and also the severity of clostridium difficile Infection, which causes fever, abdominal cramping, diarrhoea, bloating, or blood in stool.
The Imbalance in the gut causes gastro- intestinal (GI) issues that can lead to chronic constipation and alternating bowel, and this is correlated with the increased permeability to lactulose. An Increased permeability of the intestinal mucosal barrier appears to be involved in many gut/ intestine related issues such as: Inflammatory bowel disease, coeliac disease and Crohn's disease.
As result of the imbalance in the gut microbiota found in autistic patients, candida overgrowth and gastro intestinal (GI) issues can be easily explained. It is important to remember that GI issues have been linked to the pathology of autism, and also correlated with the severity in behavioural issues.
Therefore, logically thinking: controlling yeast infection can be a treatment for autism. Here is what a recent case study reported about the effects of controlling a yeast infection which resulted in the improvement of mental health issues
It is important to note that the while ADHD and autism are different neurological conditions, however they are both related in terms of the delay of certain cognitive abilities, which can lead to learning issues and even depression later in life.
In this case study reported by the Department of Psychology in the University of Canterbury in New Zealand, it was found that yeast infection impaired the recovery of a patient with a diagnosis of ADHD and depression. The subject in this study ( Kate), received for 8 weeks of a micronutrient formula, which consisted of 36 ingredients: (1) 14 vitamins, (2) 16 minerals, (3) three amino acids, and (4) three antioxidants, taken in a dose of 15 pills per day (5 pills, 3 ×/d).
Kate was then seen periodically over the next 2 years and demonstrated good maintenance of symptom changes overall, although she needed to increase her dose prior to her menstrual period. She also noted that her symptoms would gradually return when she didn’t regularly take the pills.
About 2.5 years after her participation in the trial, Kate began reporting that she was feeling increasingly unwell, experiencing (1) a chronic sore throat; (2) a constant runny nose; (3) cramps; (4) itchy toes, anus, and vagina; (5) rashes on her legs and groin area; and (6) an overall u-like feeling. Concomitantly, all her psychiatric symptoms had returned.
Kate visited her family physician, who diagnosed Kate with a vaginal yeast infection following culture testing and prescribed an antifungal cream, Micreme H (containing miconazole nitrate 2% and hydrocortisone 1%). According to Kate, the cream had no e effect on her symptoms. She then started taking probiotics and olive leaf extract.
Olive leaf extract has been reported to inhibit cancer cells, and boost immunity. While probiotics have already been proven to be an effective treatment for yeast infection and also lower stress and anxiety levels.
After 1.5 weeks on this regime, the subject’s physical and psychiatric symptoms both improved. She and her mother reported (1) improved mood and energy levels, (2) elimination of her runny nose, (3) cessation of the chronic itching of both her anus and vagina, and (4) disappearance of her rash. After 2 months, she had returned to functioning in a manner similar to her response during the trial over 2 years previously. A follow-up 6 months later confirmed maintenance of the positive gain. Over the following 6 months, it became clear based on her own and her parent’s reports that both her physical and psychiatric symptoms returned if Kate did not take the OLE.
This case study lays a foundation for future in depth researches on how controlling yeast infection can be a treatment for autism, for now it is good news to know that neurological symptoms can be ameliorated by healing the gut, which in turn avoids candida overgrowth, and can treat it once the infection has set in.