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Fatal Aplastic Anemia Caused by Epstein-Barr Virus

Anemia Epstein Barr Virus

Epstein Barr Virus is seen by medical science as a common herpetic virus with no cure. Most varieties of Epstein Barr Virus go under the radar of the immune system until they strengthen and are ready to strike. In some cases, when certain varieties of Epstein Barr Virus do strike and attack as Aplastic Anemia -- it can be fatal.


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What is Epstein Barr Virus?

Alarmingly, over 225 million Americans have some form of Epstein Barr Virus that's affecting their life. Epstein Barr Virus is a contagious herpetic virus that can either lie dormant or wreak havoc on the human body. In fact, Epstein-Barr virus has created a secret epidemic, according to Epstein Barr Expert Anthony William, NY Times Best Selling Author of the Medical Medium series.

"If you catch Epstein Barr Virus, it goes through an initial dormant period of floating around in your bloodstream doing little more than slowly replicating itself to build its numbers—and waiting for an opportunity to launch a more direct infection."

Epstein Barr Virus usually houses up in the liver to lie-in-wait but can attack other organs and joints in the body. In the case of anemia, it can even plan its assault on your blood and bone marrow.

Aplastic Anemia Is A Rare But Serious Blood Disorder

A study published in the Annals of Internal Medicine set out to determine whether Epstein-Barr virus is present in the bone marrow of patients with aplastic anemia. Aplastic anemia is a rare but serious blood disorder. If you have it, your bone marrow doesn't make enough new blood cells. Based on cancer registry data, the overall five-year survival rate of patients with aplastic anemia is about 80% for patients younger than age 20 who have a stem cell/bone marrow transplant.

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Mononucleosis Used As A Marker For Epstein Barr Virus

Five patients were studied prospectively: three who previously had infectious mononucleosis, one with a recent viral pneumonitis, and one who was asymptomatic. Stored DNA samples from other patients with aplastic anemia were also screened.

Epstein Barr Virus Strain Not The Same As Mononucleosis

Epstein-Barr virus DNA and protein were detected in the bone marrow of 5 patients studied prospectively and in 1 of 40 patients studied retrospectively. In contrast, Epstein-Barr virus DNA was not detected in peripheral blood DNA of these patients, nor were Epstein-Barr virus proteins or DNA found in the bone marrow of normal donors, patients with other hematologic diseases, or in 1 patient with acute infectious mononucleosis. Analysis of DNA fragments by hybridization with Epstein-Barr virus probes showed a pattern dissimilar to the type of Epstein-Barr virus usually associated with infectious mononucleosis, indicating they are dealing with a different variety of the disease.

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Aplastic Anemia Caused By Epstein Barr Virus

The study concluded that Aplastic anemia may be associated with Epstein-Barr virus more commonly than suspected by history. Localization of the virus in the bone marrow supports a causative role for Epstein-Barr virus in bone marrow failure.