Probiotics and Diabetes, a Possible Benefit Regarding Obesity


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Jul 23 2012 - 6:52am
Probiotics, diabetes and obesity

For several years, researchers have been exploring the role of good bacteria--probiotics--and obesity, zeroing in on the relationship between the two. Now a new review highlights the potential for probiotics to be beneficial in a disease closely associated with obesity: diabetes.

Probiotics may be good for diabetes

The human intestinal tract harbors an incredible number (estimated 10 to the 14th power) of microorganisms, collectively referred to as colonic flora or gut microbiota, and composed of both "good" and "bad" (disease-causing) bacteria. Research has suggested that the colonic flora have an impact on how the body acquires nutrients and regulates energy, and that obese and lean individuals harbor some differences in their gut microbiota.

In fact, the authors of the new review note that "Although clearly no substitute for proper diet and exercise, manipulation of the gut microbiota may represent a novel approach for treating obesity, one that has few adverse effects." For individuals who have diabetes, the possibility of using probiotics to help with weight is an appealing possibility.

These findings further suggest that gut microbiota has a role in the development of obesity and by extension, has an effect on diabetes. For example, a 2009 report in Current Pharmaceutical Design noted that "data obtained in experimental models and human subjects are in favour of the fact that changing the gut microbiota (with prebiotics and/or probiotics) may participate in the control of the development of metabolic diseases associated with obesity," of which diabetes is one.


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Prebiotics are non-digestible food products that "beneficially affect[s] the host by selectively stimulating the growth and/or activity of one or a limited number of bacteria in the colon," according to the scientists, Gibson and Roberfroid, who introduced the term in 1995. Basically, prebiotics can nourish probiotics.

Let's return to the topic of probiotics, obesity, and diabetes. Here are a few of the studies that have looked at this relationship.


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