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Memantine drug shows promise for fibromyalgia

Lana Bandoim's picture
Fibromyalgia drug

A study from Spain has found that memantine shows promise for treating some fibromyalgia symptoms. The double-blind, randomized, controlled trial of the drug followed patients for six months. The results were encouraging compared to a placebo used in the study, and side effects were limited.


Fibromyalgia is not an easy condition to treat, so studies that focus on medications or other therapies are important. Researchers discovered that patients who were given the memantine drug experienced less pain and felt better. The study had a group of 63 patients, and a placebo was also included to compare results with the medication.

After six months, scientists found that memantine reduced pain, but this was not the only benefit of the drug. Patients also reported that they felt less anxious and experienced less brain fog than the placebo group. Researchers mentioned that their sample size of 63 patients was small, but they are interested in doing more studies with more people.

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Memantine is generally used to help people with dementia and Alzheimer's disease, so it is not a regular treatment for fibromyalgia. The medication has also been used for Parkinson's disease and has been tested for other conditions. It does not cure dementia in patients, but it may slow down the disease. The drug works by blocking extra glutamate in the brain, and researchers were interested in seeing how it affected pain levels in fibromyalgia patients.

The side effects of memantine were limited in the study with patients experiencing dizziness and headaches. Other studies have found that the medication can also cause constipation, drowsiness and confusion. People with kidney disease must consult a medical professional and discuss their condition before taking this drug. If you are concerned about the medication, then you need to speak to your doctor and discuss side effects.

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