A natural compound in onions may help fight cancer

Harold Mandel's picture
Onions

Researchers at Kumamoto University in Japan say they have isolated a natural compound isolated from onions called onionin A (ONA) which has several properties that help fight ovarian cancer.

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There has been a growing awareness of the value of good nutrition to help fight cancer. Recently a compound which is from onions has been found to have anti-cancer properties.

A natural compound which is derived from onions has been found to have anti-cancer effects

Kumamoto University reports a natural compound which is derived from onions has been found to have anti-cancer effects. This compound is called onionin A (ONA) and has several properties which are anti-ovarian cancer in nature.

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The most common variant of ovarian cancer has a 5 year survival rate of about 40 percent

The most common variant of ovarian cancer has a 5 year survival rate of about 40 percent according to a review of cancer medicines by the World Health Organization. This type of ovarian cancer has a relatively low lifetime risk of less than 1 percent. Due to the fact that about 80 percent of patients have a relapse after their first treatment with chemotherapy researchers have been in search of a more effective treatment.

ONA has several effects on epithelial ovarian cancer

Researchers at Kumamoto University have discovered that ONA has several effects on epithelial ovarian cancer (EOC). ONA has been found to decrease the progression of malignant ovarian cancer tumors by disrupting the pro-tumor function of myeloid cells. Anti-tumor immune responses appear to be activated by ONA by wiping out the immunosuppressive function of myeloid cells.

There is the potential for ONA to enhance existing anti-cancer drugs

There is the potential for ONA to enhance existing anti-cancer drugs while at the same time having little to no cytotoxic effects on cells which are normal. It is hoped that with just a little more testing an oral ONA supplement will be developed which can significantly benefit cancer patients.

This study has been published in the journal Scientific Reports. ONA has been observed to inhibit the progression of ovarian cancer by suppressing the proliferation of cancer cells and the protumour function which macrophages display. ONA holds great promise in the fight against cancer.

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