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Fatty acid levels may serve as a predictor of psychosis

Harold Mandel's picture
Fatty acid level

Mental health researchers have made a promising breakthrough dealing with fatty acid levels for early detection of the risk of psychosis.


Psychosis is a very troubling state of mind wherein a person loses touch with reality. The concept of being able to predict people at increased risk for psychosis and move in to prevent a psychotic episode with nutritional factors is intriguing.

There has been a hopeful breakthrough for the early detection of the risk of psychosis

The University of Adelaide reports there is hope early detection will be able to prevent psychosis. There has been a hopeful breakthrough for the early detection of the risk of psychosis by Adelaide mental health researchers. It is hoped patients will be able to be given effective treatments earlier in order to prevent psychotic episodes from happening.

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Researchers have developed a new probability model which has shown a 70 percent accuracy rate in making a determination of patients who are at the most risk of experiencing their first episode of psychosis within 12 months. There was a 28 percent accuracy rate for making a determination of patients who are at "ultra high risk" of a psychotic episode.

Fatty acid levels may help to determine a patient's risk for psychosis

In this new model medical history is combined with the most recent bedside clinical assessment, and biomarkers of fatty acids in order to make a determination of a patient's risk of becoming psychotic. It is very significant that the critical role of fatty acids as well as mental health assessments have been taken into account in this model.

Lead author Dr Clark has noted that fatty acids such as omega-3 and nervonic acid are vital for the normal functioning of the brain. Low levels of these fatty acids have been observed to be associated with the development of psychosis in groups which are at high risk.

This study has been published in the journal Translational Psychiatry.. Fatty acid markers along with clinical assessment seems to offer a promising approach to the prediction of a psychotic break. It seems very possible that correcting low levels of fatty acids with diet and supplements may offer great promise for the prevention of psychosis.