ART and RIT May Help to Find Cure for HIV
Researchers believe it may be possible to wipe out HIV and find treatment by combining two therapies together. People have been living in fear of possibly dying horrible deaths from HIV. The statistics are alarming with over 1.1 million Americans living with HIV infection and 33.4 million people worldwide living with this deadly infection. Ever since the first cases became evident in 1981 greater than 25 million people across the world have died from AIDS.
RIT in combination with ART eliminates HIV infected cells
Research shows that RIT in combination with ART eliminated HIV infected cells, according to a research paper from the Radiological Society of North America, which was released from embargo on Dec. 3, 2013. The researchers recognized that the elimination of virally infected cells is a vital component of a successful HIV eradication strategy. Furthermore, because many patients on antiretroviral therapy (ART) suffer from HIV associated neurocognitive disorders, drugs which can enter into the CNS and wipe out the infection are necessary. With radioimmunotherapy (RIT) cells are killed using radiolabeled monoclonal antibodies (mAbs).
The researchers discovered that RIT was capable of specifically killing ART treated lymphocytes and reducing HIV to levels which are not detectable. The bottom line is RIT used with ART wiped out infected cells. These results have demonstrated the possibility of developing an RIT based strategy for use with ART to achieve HIV eradication.
At this time HIV/AIDS remains an incurable disease. These researchers are continuing to work to develop RIT based strategies for use with other anti retroviral strategies with a goal of achieving complete HIV eradication. There is also work being done to develop an effective AIDS vaccine, writes EmaxHealth reporter Tyler Woods Ph.D.
Understanding what HIV stands for is simple
AIDS.gov breaks down what HIV is to help with a clear understanding of what this infection is, as follows:
H – Human – This particular type of virus can only infect human beings
I – Immunodeficiency – HIV weakens your immune system by destroying vital cells that fight disease and infection.
V – Virus – A virus can only reproduce itself by actually taking over a cell in the body of its host
Although HIV has many traits in common with other viruses, such as those which cause the "flu" or the common cold, there is an important difference. Your immune system has the capacity to clear most viruses out of your body. However the human immune system can't seem to clear the body of HIV. Your T-cells, or CD4 cells, are a vital part of your immune system. HIV invades these cells which are needed to fight infections and disease. Eventually HIV can destroy so many of your CD4 cells that your body can no longer fight infections and diseases. This is how HIV infection becomes AIDS.
An understanding of what AIDS stands for is simple
There is a simple way to understand the basics of what AIDS is, as follows:
A – Acquired – AIDS is not something you inherit from your parents, it is something you acquire after birth
I – Immuno – Your body's immune system includes all the vital organs and cells that work to fight off infection or disease
D – Deficiency – AIDS develops when your immune system is "deficient," or is not working the way it should be working
S – Syndrome – A syndrome is a collection of symptoms and signs of a disease. AIDS is defined as a syndrome, instead of a single disease, because it is a complex illness which has a wide range of complications and symptoms
The final stage of HIV infection is AIDS, at which time people have badly damaged immune systems, which leaves them at risk for opportunistic infections. It is believed by scientists that
HIV came from a particular type of chimpanzee in Western Africa. People probably came into contact with HIV when they hunted and ate the infected animals. It now appears that HIV may have skipped over from monkeys to people as far back as the late 1800s.
HIV infection comes from bodily fluids
You can become infected with HIV if body fluids infected with HIV enter your body. The following fluids can contain high levels of HIV:
3: Pre-seminal fluid
4: Breast milk
5: Vaginal fluids
6: Rectal mucous
7: Amniotic fluid
8: Cerebrospinal fluid
9: Synovial fluid