Bacteria in soil may hold the key to successful treatment of TB
Researchers say new candidates for TB drugs can be developed from bacteria in soil.
Tuberculosis (TB) is a serious illness caused by the a bacterium which is called Mycobacterium tuberculosis. This bacteria generally attacks the lungs and can be fatal. Researchers have been investigating new treatments for TB.
New drug candidates for TB are being developed from bacteria in the soil
The University of Warwick reports new drug candidates for TB are being developed from bacteria in the soil. A new compound which has been created from bacteria in the soil which is effective in preventing other bacteria from growing around them has been found to effectively kill Mycobacterium tuberculosis.
In 2015 there were estimated to be 10.4 million new cases of TB with 1.4 million deaths
The finding of a new treatment for TB is very significant in view of how widespread and serious this illness is. In 2015 there were estimated to be 10.4 million new cases of TB with 1.4 million deaths from this infectious disease. TB has been particularly hard to treat in many cases due to increasing resistance to standard treatments developing in TB bacteria. There were more than 250,000 deaths in 2015 from TB infections which were drug resistant.
An international team of researchers from Australia, Canada and the USA working with University of Warwick researchers has discovered a compound made from bacteria which live in soil which may be able to be used in a new drug for TB. Potent chemical analogues which kill Mycobacterium tuberculosis have been developed by these scientists from soil bacteria compounds.
This study has been published in Nature Communications. There is large global morbidity and mortality from TB. Due to growing resistance to drug therapies which have been used for more than 40 years there has been a desperate need for new drugs which can effectively treat TB. New drug analogues derived from bacterium in the soil seems to offer hope for a new powerful treatment for TB.