How a specific fat type can protect against weight gain and diabetes

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Diabetic Diet

A new study from Joslin Diabetes Center may shed light on why some people can eat excessive amounts of food and not gain weight or develop type 2 diabetes, while others are more likely to develop obesity and this most common form of diabetes on any diet. The study, which used two strains of mice with differing tendencies to gain weight and develop diabetes on a high-fat diet, identified genetic and cellular mechanisms that may prevent certain mice on a calorie-dense diet from gaining weight and developing metabolic syndrome.

"Although this study was done with mice, it points out new mechanisms that may underlie the ability of genetically different mice - and perhaps genetically different people -- to not gain much weight on high caloric diets," said lead investigator C. Ronald Kahn, M.D., an internationally recognized researcher who is Head of Joslin

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