Addiction Drug Can Also Treat Obesity
Addiction treatment drug Vigabatrin is found to be good as obesity treatment.
Vigabatrin is addiction drug, which took 20 years to be developed. It comes from scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and now is being examined by U.S. Food and Drug Administration. The drug is now undergoing Phase II clinical trials and will soon seek approval as cocaine and methamphetamine addiction treatment.
It was previously known that drug addiction is closely linked to obesity, and since obesity is a major problem for all developed countries, scientists decided to test Vigabatrin as obesity treatment as well.
Researchers looked at 50 animals, who either had normal weight or were genetically fat. Animals were divided into groups according the drug dosage they received. The first group of animals was receiving daily injections of salt water, the other groups were receiving 300mg, 150mg, and 75mg doses of Vigabatrin. All animals were receiving injections for two phases of 7-13 day periods, the periods were separated with short pauses.
Animals were followed for 40 days and were found to lose weight magically. Those taking higher doses of Vigabatrin lost more weight than those on lower doses. Obese animals lost 19% of their weight, while non-obese animals lost from 12 to 20 percent of their weight. Animals also consumed less food, but were quite satisfied with what they ate.
The fact that study animals were genetically fat and they managed to lose weight shows, that Vigabatrin is strong enough because it is more difficult to lose weight for genetically overweight animals than for those who are fat because of environmental causes.