Resveratrol in grapes stimulates obesity fighting hormone

Kathleen Blanchard's picture

Resveratrol properties for fighting obesity have been found by researchers.

Scientists have discovered the health compound, a polyphenol, found in grapes stimulates an important fat regulating hormone known as adiponectin that is linked to obesity.

The hormone has many health benefits, some of which have recently been discovered. Adiponectin stimulates appetite, helps control blood sugar levels and is found to be lower in obese individuals. In mice fed a high fat diet, higher levels of adiponectin made them resistant to obesity.

Higher levels of adiponectin produced by resveratrol could mean less risk for type 2 diabetes, heart disease and even cancer.


Senior author Feng Liu, Ph.D., professor of pharmacology and member of the Barshop Institute of Longevity and Aging Studies at University of Texas Health Science Center confirmed findings that resveratrol stimulates adiponectin in lab and mouse studies that could lead to obesity treatment options.

Liu says, “Results from these studies should be of interest to those who are obese, diabetic and growing older.” He also says understanding how resveratrol stimulates the beneficial fat hormone could lead to new treatment options for the conditions and other age-related illnesses.

Last year the same researchers made an important anti-aging discovery that shows resveratrol stops activity of the mammalian target of rapamycin (mTOR). Mice were found to live longer with decreased TOR activity, leading scientists to pursue the mTOR pathway response for clues that might help people live long, healthy, disease free lives.

Resveratrol is shown to have many health benefits. It is found naturally in grapes and is linked to the health benefits of drinking red wine. The new findings show resveratrol stimulates the beneficial fat hormone adiponectin that can help fight a variety of diseases brought about by obesity.

Journal of Biological Chemistry: doi: 10.1074/jbc.M110.188144



keep up the good work for mankind