Natural formula shows promise for aggressive prostate cancer
A natural formulation of just the right nutrients might stop aggressive forms of prostate cancer that are resistant to hormone deprivation therapy, according to results of in vivo studies presented at the 16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine.
Researchers at the Methodist Research Institute at Indiana University say the; formula suppressed prostate tumor growth in mice, in addition to disarming two genes linked to metastasis of the disease.
The natural formula is made up of compounds known to support prostate health and includes antioxidants, biomedically enhanced medicinal mushrooms and phytonutrients.
Lead investigator of the study, Dr. Daniel Sliva, presented study results, showing the all-natural ingredients in the formula work to stop the spread of (androgen independent) prostate cancer cells, compared to controls.
For this study, the researchers used a xenograft mouse model.
“Dietary supplements are used as an alternative or adjuvant therapies. However, rigorous scientific verification of their biological activity in vitro and in vivo is necessary for the acceptance of dietary supplements in conventional cancer treatment and prevention,” says Dr. Sliva.
The formula has also been studied in cell cultures at Columbia University, NY, NY and at the Cancer Research Laboratory, Methodist Research Institute, Indiana University Health, Indianapolis, Indiana, in addition to gene expression analysis. The studies showed the antioxidant, mushroom, phytonutrient formula inhibited the growth and spread of prostate cancer.
The researchers are planning to continue their studies. The formula shows promise as a natural treatment for aggressive prostate cancer.
“In summary, this dietary supplement is a natural compound for the possible therapy of human hormone refractory (independent) prostate cancer,” says Dr. Sliva. Ongoing research on this formula in prostate cancer models continues to show encouraging results, and additional studies are forthcoming.”
If the natural formula shows success in ongoing studies, it would prove to be a breakthrough for prostate cancer treatment that also is non-toxic. For more information about the study, you can call (707) 583-8622 or email [email protected].
Integrative Cancer Therapies
doi: 10.1177/1534735410371478Integr Cancer Ther June 2010 vol. 9no. 2 186-196
“ProstaCaid Induces G2/M Cell Cycle Arrest and Apoptosis in Human and Mouse Androgen-Dependent and-Independent Prostate Cancer Cells”
Jun Yan, PhD
Int J Oncol. 2011 Jun;38(6):1675-82. doi: 10.3892/ijo.2011.996. Epub 2011 Apr 4.
“Suppression of growth and invasive behavior of human prostate cancer cells by ProstaCaid™: mechanism of activity”
Jiang J, Eliaz I, Sliva D.
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