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Lingering food poisoning bacteria linked to cause of Crohn's disease

Kathleen Blanchard's picture
Food poisoning bacteria linked to Crohn's disease

New research suggests the cause of Crohn's disease could be gut bacteria that lingers after a bout of food poisoning has occurred.


The finding could have implications for helping to predict who is at risk for Crohn's disease later in life, according to McMaster University researchers.

Finding Crohn’s disease cause could mean fewer people develop the bowel disease

Brian Coombs, a McMaster University researchers led the study. Coombs is a professor of biomedical and biochemical sciences says the need to find prevention and treatment for Crohn’s disease has never been more “pressing”.

Crohn’s disease is a lifelong ailment that leads to significant decreased quality of life increases a person’s risk for colon cancer and often strikes at a young age. The inflammatory condition also boost the risk of dying from complications associated with the autoimmune disease, the researcher adds.

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The finding, published in the journal PLOS pathogens, highlights the study that was performed on mice and shows a common bacteria that causes food poisoning might set off a lingering effect that leads to a higher risk of Crohn’s disease later in life.

The mouse model used in the study suggested food poisoning causes an increase in the growth of adherent-invasive E. coli (AIEC).

E.coli has been associated with Crohn’s disease development.

The researchers found even after food poisoning was eliminate, the mice continued to have worsening symptoms from the gut bacteria.

If the finding is supported by further researcher, it could lead to better treatments for Crohn’s disease. Ideally, the condition could be preventable.

Image credit: Wikimedia Commons