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Black Seed Oil Compound Kills Prostate Cancer Cells in Lab Study

Kathleen Blanchard's picture
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Black seed oil from the Nigella sativa plant is found to kill prostate cancer cells, found in lab studies. Researchers from Tulane University have shown that Thymoquinone (TQ) has anti-cancer properties that suppress the growth and lead to death of aggressive prostate cancer cells. The discovery comes from the scientists desire to find natural compounds with anti-cancer properties.


According to Dr. Debasis Mondal who was part of the research team, “Complementary and alternative medicine (CAM) is becoming very important as an adjunct therapy in cancer patients, both to ameliorate the side effects of chemotherapy as well as to enhance their anti-tumor effects. The low side effect profiles of natural compounds is also an important aspect in their therapeutic utility as an adjunct to anti-tumor therapy.”

The researchers recognized that Thymoquinone in black seed oil (Nigella sativa) has a similar effect to the compound ubiquinone or co-enzyme Q that is also an essential nutrient produced by the body. They found that Thymoquinone rapidly generates reactive oxygen species (ROS) in particularly aggressive types of LNCaP and C4-2B prostate cancer cells. Cancer cells that are resistant to chemotherapy are found to have high levels of glutathione (GSH) that also decreased with exposure to the black seed oil compound.

The research suggests it is the combined action of ROS induction and inhibition of glutathione levels from Thymoquinone found in black seed oil that leads to death of prostate cancer cells. Dr. Steven R. Goodman, Editor-in-Chief of Experimental Biology and Medicine says the researchers… “have demonstrated that Thymoquinone efficiently killed hormone-dependent and hormone-independent prostate cancer cells. The mechanism appears to be that Thymoquinone induces oxidative stress and suppresses GSH levels. This suggests that oxidative stress may lead to decreased tumor growth and increased cell death in highly aggressive forms of prostate cancer."

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Thymoquinone, found in black seed oil (Nigella sativa) has been shown to kill pancreatic cancer cells, colon cancer, and has been examined for its potential in the treatment of breast cancer. The new study demonstrated that Thymoquinone killed aggressive prostate cancer cells in lab studies and may prove to be an adjunctive therapy that can treat aggressive forms of prostate cancer.

Journal reference:

P. S. Koka, D. Mondal, M. Schultz, A. B. Abdel-Mageed, K. C. Agrawal. Studies on molecular mechanisms of growth inhibitory effects of thymoquinone against prostate cancer cells: role of reactive oxygen species. Experimental Biology and Medicine, 2010; 235 (6): 751 DOI: 10.1258/ebm.2010.009369

Updated 3/11/2017



I would like ro buy this!
I spoke with my alternative doctor and he said that black seed oil needs to be taken about three times a day and to keep it in the system. I am not sure that this will work entirely so I bought the fourth edition of Bill Henderson's book "Beating Cancer Gently". It is an awesome, awesome book that actually gives a protocol to follow. My husband and I took the cancer test that he spoke of in the book and it appears that we both have some form of cancer. We are following the protocols almost exactly and we will take the test again in three months. It is such a relief to have a plan!! We are taking the black seed oil three times a day with meals.
I have been dealing with Elevated PSA numbers for the last 4 years and doctors that only want to do a biopsy, and Yada Yada Yada. I have been doing infused Black Seed Oil with Saffron, mixed at 15 grams of Saffron to 350mL of BSO. I take a 1 teaspoon in the morning on an empty stomach, and 1 in the evening a couple of hours after dinner. No more waking up 2 or 3 times at night to urinate, no more urgency to go during the daytime, and best of all, my PSA numbers are dropping. As an added bonus, my A1C and cholesterol numbers normalized. I was borderline diabetic as well, but no more. I have only been doing this BSO for about 6 weeks, but this looks very promising to me. Buy a good quality BSO, cold pressed virgin oil and don't scrimp on the Saffron. This is your health you're dealing with.
Dear Sirs, I would like to try the Elixer Vitae for my Prostate Cancer. I would be grateful if you could tell me where to get it and the serving size, and also the amount of doses per day. Best regards, Ross McKay