Turmeric Delays Liver Disease Progression

Kathleen Blanchard's picture
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Scientists have found that the Indian spice turmeric delayed the progression of liver disease associated with autoimmune disease known as primary sclerosing cholangitis (PSC) and primary biliary cirrhosis. Turmeric, known for its anti inflammatory and antioxidant properties, stopped liver damage in mice that ultimately leads to cirrhosis.

Researchers say that turmeric is a natural product that could be useful for treating a variety of inflammatory diseases because it blocks chemical pathways involved in inflammation.

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PSC affects approximately 6 per 100,000 individuals and primarily men. The average age of onset is 40. The liver disease often occurs in association with Crohn’s disease. PSC is a rapidly progressing disease. Primary biliary cirrhosis is also thought to be the result of autoimmune dysfunction that slowly destroys the bile ducts in the liver that carry digestive fluids that rid the body of cholesterol and toxins and can lead to scarring and cirrhosis of the liver. Both diseases can be fatal.

Turmeric, added to the diet of mice, was found to significantly reduce liver scarring and damage in mice fed turmeric for four to eight weeks, and was compared to a group not given turmeric in the diet.

Inflammatory liver disease can progress and be fatal. Current treatment of primary biliary cirrhosis includes the use of ursodeoxycholic acid, but the long term effects remain controversial. Liver transplant is the only other alternative. Turmeric could be a promising treatment for autoimmune liver diseases that are difficult to treat and can be fatal. The Indian spice has been studied for its beneficial role in reducing inflammation that leads to a variety of diseases.

BMJ-British Medical Journal

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Comments

THANK YOU!!! I was diagnosed with PBC 6 years ago and have searched ever since then for SOMETHING to support my belief that I can beat this disease. It is extremely rare to find any information that supports anything other than Ursodol. I intend to be proof that this too can be fixed by nutrition, lifestyle and mindset.
Stephanie, you are most welcome. Sending healing thoughts to you. I am proud that you are researching and taking positive steps.
My daughter has had PSC for 5 years and this news is amazing. Please advise should she start taking turmeric now and if so how much and in what form?
I have been diagnosed with PBC in 2012. I would like to know how to take turmeric and in what quantities. Some recipes would also be beneficial.
You must talk to your doctor. More studies on humans are needed.This was an animal study.
You must talk to your doctor. More studies on humans are needed.This was an animal study.
I was diagnosed with PBC 2-1/2 years ago and it had progressed to liver cirrhosis, stage 4. I started on Ursodiol two years ago but also started adding turmeric to my diet. I don't take a specific amount but I add it to my breakfast every morning (oatmeal or cottage cheese, apples, nuts, seeds) and also to green smoothies, which I also started to drink regularly. (I just throw all kinds of green veggies and water into a blender...make sure to add 1/2 an avocado so it's creamy.) All in all I probably have about a teaspoon of turmeric a day. I have blood tests done twice a year to check my liver enzyme levels. They came down steadily until this past spring they were completely normal. I also have an abdominal ultrasound done twice a year because I'm told that cirrhosis increases the risk for liver cancer. The ultrasounds only show a couple of cysts which are harmless. Anyway, this past spring I had another Fibroscan to check my cirrhosis and was stunned to hear that I no longer have cirrhosis at all. I went from stage 4 cirrhosis to stage 2 (fibrosis). Fibrosis is reversible. So yes, I'm a big believer in turmeric and also in green smoothies. Nowadays I also cut out eating sugar except on very rare occasions. Sugar is very inflammatory and we want to avoid that! Good luck to you all and don't give up hope!