Pomegranate Juice may Slow and Prevent Prostate Cancer
New research shows that men treated for localized prostate cancer may benefit from drinking pomegranate juice. Results of a long-term study show that men who drank eight ounces of pomegranate juice daily had slower progression of untreatable localized prostate cancer.
Researchers compared 48 men with prostate cancer enrolled in the stage 2 clinical trial, following the men for six years. The group of men had undergone either surgery or radiotherapy for prostate cancer. Criteria for entrance into the study included PSA above 0.2 ng/ml and less than 5 ng/ml and a Gleason score of 7 or less.
At the start of the study, all of the men showed increased PSA levels. During the six-year follow-up, men who remained active in the study, consuming pomegranate juice, showed slower progression of prostate cancer, evidenced by lower PSA levels.
Christopher Amling, MD, an American Urological Association spokesperson says, “This study suggests that pomegranate juice may effectively slow the progression of prostate cancer after unsuccessful .treatment. This finding and other ongoing research might one day reveal that pomegranate juice is an effective prostate cancer preventative agent as well."
Phase 3 trials are underway to determine if pomegranate juice is more effective for slowing prostate cancer in some men than others. The researchers say parts of the study suggest that some men are more sensitive to the effects of pomegranate juice on decreasing PSA doubling time. The phase 3 trial will compare pomegranate juice to placebo to clarify the effects of pomegranate juice on slowing and possibly preventing prostate cancer.
J Urol, suppl. 2009: 181, 4, abstract 826.