Children With Bowel Disease Experience High Folate Levels
Surprisingly high folate levels have been found in the blood of children newly diagnosed with inflammatory bowel disease (IBD), a finding that questions the theory that IBD patients are prone to folate deficiency, U.S. researchers say.
IBD, which includes Crohn's disease and ulcerative colitis, can cause abdominal pain, diarrhea, fever, bleeding and nutritional deficiencies. Previous studies found that adult IBD patients often have lower folate levels than those without the condition, United Press International reported.
"However, pediatric inflammatory bowel disease appears to be somewhat different from the adult form, and before this study very little was known about folate levels in newly diagnosed children with the disease," study senior author Nina Holland said in a news release.
"This is exciting work that opens the door to additional research into the role of folic acid and its genetic basis in the development of inflammatory bowel disease, especially in young patients," added study co-author Dr. Melvin Heyman, UPI reported.
The study appears in the February issue of the American Journal of Clinical Nutrition.