Bipolar Disorder

Bipolar Disorder In Children, Teens

ruzik_tuzik — Mon, 17 Nov 2008 13:38:40 -0600

Does your child go through intense mood changes?

Does your child have extreme behavior changes too? Does your child get too excited or silly sometimes? Do you notice he or she is very sad at other times? Do these changes affect how your child acts at school or at home?

Some children and teens with these symptoms may have bipolar disorder, a serious mental illness. Read this brochure to find out more.

What is bipolar disorder?

Symptoms Persist As Bipolar Children Grow Up

ruzik_tuzik — Wed, 29 Oct 2008 06:01:08 -0500

Bipolar disorder (BD) identified in childhood often persisted into adulthood in the first large follow-up study of its kind. Forty-four percent of children diagnosed with BD continued to have manic episodes as adults, in the study by NIMH grantee Barbara Geller, M.D., and colleagues at Washington University in St. Louis. They report on their findings in the October issue of the Archives of General Psychiatry.

AstraZeneca’s SEROQUEL XR for the treatment of bipolar depression, mania

hareyan — Fri, 10 Oct 2008 14:27:44 -0500

AstraZeneca (NYSE: AZN) today announced that the U.S. Food and Drug Administration (FDA) has approved once-daily SEROQUEL XR® (quetiapine fumarate) Extended-Release Tablets for the acute treatment of the depressive episodes associated with bipolar disorder, the manic and mixed episodes associated with bipolar I disorder, and the maintenance treatment of bipolar I disorder as adjunctive therapy to lithium or divalproex. SEROQUEL XR is the first medication approved by the FDA for the once-daily acute treatment of both depressive and manic episodes associated with bipolar disorder.1

ECNP releases consensus statement on bipolar depression

hareyan — Sun, 31 Aug 2008 20:58:08 -0500

Bipolar disorder is one of the most important psychiatric diseases, often associated with considerable treatment needs and tremendous social and occupational burden for both the individual and family (Pini et al., 2005). Previously also labelled manic-depressive illness, bipolar disorder is typically referred to as an episodic, yet lifelong and clinically severe mood (or affective) disorder.

Study Implicates Gene Abnormalities In Bipolar Disorder

ruzik_tuzik — Wed, 20 Aug 2008 09:33:17 -0500

The largest genetic analysis of its kind to date for bipolar disorder has implicated machinery involved in the balance of sodium and calcium in brain cells. Researchers supported in part by the National Institute of Mental Health, part of the National Institutes of Health, found an association between the disorder and variation in two genes that make components of channels that manage the flow of the elements into and out of cells, including neurons.

New Treatments For Bipolar Disorder Found

ruzik_tuzik — Mon, 07 Jul 2008 08:26:35 -0500

For the 5.7 million Americans with bipolar disorder, finding effective treatments can pose a serious challenge. But recent research has shown promise for expanding the number of medicines that can be used to prevent the manic “highs” and depressed “lows” that characterize this condition.

Potential New Target For Developing Medications To Treat Bipolar Disorder

ruzik_tuzik — Tue, 01 Jul 2008 08:18:29 -0500

Medications that target the protein BAG1, which regulates a process that can trigger symptoms in people who have bipolar disorder, may offer a new way of treating the disease, according to NIMH scientists.

People with bipolar disorder, also called manic depressive illness, experience unusually intense emotional states that occur in distinct periods called mood episodes. An overly joyful or overexcited state is called a manic episode, and an extremely sad or hopeless state is called a depressive episode.

Bipolar Disorder: Epidemic Without A Disease

hareyan — Wed, 11 Jun 2008 09:27:30 -0500

In any report of an epidemic there should be a description of the disease of which the epidemic is comprised and mention of the test by which the disease is diagnosed. But nowhere is there mention of a physical abnormality-gross, microscopic or chemical, to make it a disease.

FDA Approves Seroquel For Maintenance Treatment In Bipolar Disorder

hareyan — Thu, 15 May 2008 08:21:29 -0500

AstraZeneca announced FDA has approved SEROQUEL for the maintenance treatment of patients with bipolar I disorder, as adjunct therapy to lithium or divalproex.

Do Doctors Overdiagnose Bipolar Disorder?

hareyan — Tue, 06 May 2008 08:53:09 -0500

Fewer than half the patients previously diagnosed with bipolar disorder received a diagnosis of bipolar disorder based on a comprehensive, psychiatric diagnostic interview.