EmaxHealth Health News
Home » Cancer Treatment » Breast Cancer

New Breast Cancer Drug Tykerb From Glaxo May Be Within Months In EU

Ads by Google

All About:
  • Breast Cancer

By Armen Hareyan on October 8, 2006 - 7:00pm for eMaxHealth

Glaxo is set to file for EU approval of it's new breast cancer drug Tykerb, reports The Observer.

While the source is not named in the report, it says that unlike Swiss made Herceptin - which is administered intravenously - the breast cancer drug Tykerb from GSK offers a significant advance in treatment because women can swallow one pill a day at home.

Recently GSK announced the submission of a New Drug Application (NDA) to the United States Food and Drug Administration (FDA) for approval to market Tykerb (lapatinib ditosylate), in combination with Xeloda (capecitabine), for the treatment of advanced or metastatic HER2 (ErbB2) positive breast cancer in women who have received prior therapy, including Herceptin (trastuzumab).

From the press release we learn the following about the breast cancer drug Tykerb:

Tykerb, a small molecule that is administered orally, inhibits the tyrosine kinase components of EGFR (ErbB1) and HER2 receptors. Stimulation of EGFR and HER2 is associated with cell proliferation and with multiple processes involved in tumor progression, invasion, and metastases. Overexpression of these receptors has been reported in a variety of human tumors and is associated with poor prognosis and reduced overall survival.

GSK is using advanced technologies, including pharmacogenetics, to better define patient populations that may respond to Tykerb.

The compound has been granted Fast Track status by the FDA in this patient population. TYKERB is a small molecule dual kinase inhibitor developed by GSK as an oral therapy, and is currently being investigated in breast cancer and other solid tumors. TYKERB is an investigational drug and has not been approved for marketing by any regulatory body.

Source: 
eMaxHealth

eMaxHealth welcomes yourcomments and feedback on this story without registration, but keep the comments meaningful please. Links are not accepted.

  • Add new comment

Similar Stories

  • Breast cancer preventative reported to weaken bones
  • Girls Born to Older Mothers Have Increased Risk of Breast Cancer
  • Komen foundation reverses Planned Parenthood decision
  • Komen Foundation cuts off funding to Planned Parenthood
  • Cancer Vaccine Eliminates Tumors in Early Breast Cancer

 Dr. Oz Promotes Magnet Cure
 Skin Care Secrets in Your Kitchen
 3 Gadgets to Make You Look 10 Years Younger
 Catalase is the Culprit for Gray Hair
 Vibration Therapy Helps Chronic Pain
 What If Antidepressants Don't Work
 When Obesity is OK for Some

Health Categories

 EMAXHEALTH HOME
 AFFORDABLE HEALTH INSURANCE
 DIET & WEIGHT LOSS
 FITNESS & EXERCISE
 MEN'S HEALTH
 WOMEN'S HEALTH
 BEAUTY
 ALTERNATIVE MEDICINE
 CANCER TREATMENT
 AGING
 DISEASE and CONDITION
 MENTAL HEALTH
 GENERAL HEALTH
 PERSONAL HEALTH
 GOURMET FOOD & HEALTH
 HEALING & SPIRITUALITY
 MONEY AND HEALTH
 Comment Moderation
  • Health RSS Feeds
  • Privacy Policy
  • Disclaimer
  • About Us
  • Editorial Review Process
  • Advertise
  • Contact
  • Contributors
Copyright eMaxhealth.com 2005-2012. All rights reserved.

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.