Drug Clinical Trials

Pan-Harvard Program Will Catalyze Clinical Research

The Harvard Catalyst is a pan-University collaborative effort committed to harnessing the human, technological, and fiscal resources of Harvard and its academic healthcare centers (AHCs) to reduce the burden of human illness.

Truth, Consequences, Enrollment In Clinical Trials

Knowing about financial relationships between medical researchers and the companies that sponsor their studies has little effect on most patients considering enrolling in a clinical trial.

Researchers Seek Participants For Antibiotic Use Study

Researchers conducting a study to learn if children with a urinary tract disorder known as vesicoureteral reflux should be treated with an antibiotic for an extended period of time are seeking to enroll more participants.

Peptimmune Initiates Trial Of PI-2301 In Multiple Sclerosis Patients

Peptimmune a privately held biotechnology company, announced that physicians have treated the first participant in a clinical trial to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of PI-2301 in subjects with Secondary Progressive Multiple Sclerosis.

MEDIHONEY Eradicates MRSA From Chronic Venous Ulcers

MEDIHONEY has been found in a large randomized controlled clinical trial to significantly reduce the presence of methicillin-resistant Staphylococcus aureus in chronic wounds.

Effectiveness Of Blood Substitute Examined In Large Clinical Trial

In a recently concluded Phase 3 multicenter clinical trial, academic and industry researchers found the use of up to three units of a blood substitute to be relatively safe in patients under 80 with a moderate need for transfusions.

APD125 Trial For Insomnia Treatment Shows Positive Results

Dr. Thomas Roth of Henry Ford Hospital presented data from Arena's positive Phase 2a clinical trial of APD125 for the treatment of insomnia.

Sequential R-CHOP, Ibritumomab Tiuxetan Regimen Produces Impressive Survival Rates

Results of an investigator-sponsored trial of the investigational regimen consolidating rituximab-CHOP with 90Yttrium Ibritumomab Tiuxetan radioimmunotherapy in high risk, elderly patients with previously untreated high-intermediate and high risk diffuse large B-cell lymphoma are promising.

Trial Demonstrates High Response Rate In Lymphoma Patients

Pharmacyclics announced final data from a Phase 1/2 study showing a 46 percent complete response rate in patients with multiply recurrent non-Hodgkin's lymphoma (NHL).

R788 Shows Benefit In Diffuse Large B-Cell And SLL/CLL

Rigel reported an abstract providing preliminary results of a Phase 2 clinical trial of its oral Syk inhibitor, R788, in patients with relapsed or refractory B-cell non-Hodgkin's lymphomas.