California Poppy for Pain, Does it Really Work?
On a recently televised health program, an alternative medicine/naturopath physician promoted the claim that an extract of the California Poppy is a little-known, but safe and effective pain reliever that the pharmaceutical industry does not want the public to know about.
In his promotion he discusses its availability and low cost in health food stores and that it requires only 3/4 of a teaspoon per night that will not only help people with their muscleoskeletal pain, but will work as a safe sleep-inducing aid as well. He stated that multiple studies have shown that this is an effective medicine and that the drug industry is not interested in it because it cannot patent a natural product.
While the patenting of pharmaceuticals is a complex process and there is no easy way to determine a company’s real reason for not pursuing a potentially effective medication, what is easier to do is to search for relevant studies to see if there is scientific support for the claim that the California poppy is a pain reliever. The following is a summary of two studies that are most likely the “multiple studies” claim made in support of the California Poppy extract by promoters of the herbal drug.
Plant Medica article
In the journal Plant Medica, a journal of medicinal plants and natural product research, researchers published a 1991 study that investigated the analgesic effects and sedative properties of the California Poppy—Eschscholzia californica. The basis for their research of these properties was due to reports that Native Americans in the rural areas of California used the plant in their traditional medicine for pain relief.
In the study, mice were administered a range of doses of aqueous extracts of the plant, and their behaviors observed as they were put to tests commonly used when analyzing the anxiolytic effects of potential anti-anxiety drugs.
One of the tests performed involved isolating an extract-treated mouse in a box with a small stairway. Apparently, the less anxious a mouse feels due to the sedative-like effects of the extract, the higher it will climb up the steps in comparison to non-treated mice.
What the researchers determined was that a relatively high dose of aqueous extract derived from the California Poppy induced the mice to sleep, while lower doses appeared to decrease the anxiety in treated mice and led them to climb higher up the stairway than non-treated mice.
The authors of the paper also noted that there did not appear to be any toxic side effects from the extract.
Current Medical Research and Opinion article