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Crohn's and Colitis

Common food ingredient linked to Crohn's, colitis

2015-03-06 10:34
Food emulsifiers that are widely used linked to colitis, Crohn's disease.

New research suggests emulsifiers that are in the bread you eat every day and in a wide variety of other foods may be contributing to chronic inflammation of the gut that leads to Crohn's disease, ulcerative colitis, metabolic syndrome, type 2 diabetes and more.

Researchers studied the effect of polysorbate 80 and carboxymethylcellulsose in mice to find the emulsifiers promote inflammation.

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Zebrafish provide insights into how Crohn's disease and colitis develop

2015-02-21 12:23
Duke University researchers uncover epigenetic changes that lead to IBD, thanks to zebrafish

Researchers know that people with inflammatory bowel disease have higher levels of tumor necrosis factor or TNF that is an inflammatory cytokine. Therapy for Crohn's disease and ulcerative colitis is geared toward inhibiting the pro-inflammatory protein to control symptoms. New information from Duke researchers gives insights into epigenetic changes that cause up-regulation of TNF and inflammation associated with the bowel disorders, thanks to zebrafish.

For their study published in the Proceedings of the National Academy of Sciences,.the researchers used zebrafish that are transparent as embryos to visualize changes in the gut that occur in respon

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Global initiative underway to find cause of Crohn's disease

2015-01-22 06:29
Researchers turn to families to find cause of Crohn's disease

International researchers are teaming up to explore what factors lead to Crohn's disease. Many questions remain about the autoimmune disorder that is difficult to manage and incurable. Scientists from Canada and Scotland are coordinating efforts to uncover why Crohn's disease is on the rise. The scientists are looking at families for help understanding IBD.

The hope is that understanding how Crohn's disease develops will lead to better treatments. Crohn's disease has doubled in young people in Scotland every decade for the past 40-years.

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Natural protein could help spare IBD patients from surgery

2015-01-19 21:05
Natural protein studied for helping reduce fibrosis from IBD

Patients diagnosed with inflammatory bowel disease often develop scarring that leads to narrowing or stricture of the colon. Researchers recently studied a natural protein that might be developed to help limit the amount of intestinal scarring from Crohn's disease and ulcerative colitis, helping spare patients from the need for surgery.

IBD can often lead to repeated surgeries. Quelling inflammation in the colon is a goal of treatment.

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New Crohn's disease damage index tool could help minimize complications

2015-01-12 13:31
New index developed by international team to measure Crohn's disease damage

Crohn's disease affects everyone differently. Sometimes the damage causes by the form of inflammatory bowel disease is difficult to measure, making it difficult to minimize complications. A new scoring index has now been created by researchers that measures the total damage to the intestines caused by Crohn's disease.

The scoring tool, known as the Lémann Index, was developed by the International Program to Develop New Indexes in Crohn’s Disease (IPNIC) group and is the first tool to take into account the extent

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Friendly yeast gobbling bacteria could help treat Crohn's disease

2015-01-10 10:22
Yeast gobbling bacteria could help Crohn's disease

Researchers from the UK and American recently discovered how a yeast gobbling bacteria could help treat Crohn's and other autoimmune diseases. For the first time, scientists have pinpointed a specific immune boosting bacteria that is stimulated when we consume bread,beer and other fermented or yeast containing foods rich in carbohydrate.

The researchers discovered how Bacteroides thetaiotaomicron that is a dominant human gut bacteria could contribute to nourishing the cells in the intestine to provide a protective effect against Cr

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Obesity clearly linked to Crohn's and other autoimmune diseases

2014-11-10 12:46
Obesity the newest factor to add to list of risk factors for Crohn's and other autoimmune diseases

New research suggests obesity could be a major contributor to Crohn's disease, multiple sclerosis and other autoimmune diseases that are the result of the the immune system attacking the body. The result of the investigation shows obesity could also prolong the effects of autoimmune diseases that also appear to be triggered by additional environmental factors.

What the researchers from Tel Aviv University found is that obesity creates a "pro-inflammatory" environment that can trigger Crohn's disease, MS and other autoimmune diseases in addition to hamper

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Sleep and ulcerative colitis have something in common

2014-11-05 21:27
Too much, too little sleep linked to ulcerative colitis

A recent investigation from researchers at Massachusetts General Hospital suggests sleep duration may be an important factor when it comes to both preventing and managing ulcerative colitis that affects one million people worldwide.

Results of a new investigation suggests sleeping too little might increase a person's risk of developing UC in addition to causing flare-up.

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CCFA partners with celebrity cook to help Crohn's, colitis patients

2014-10-26 10:46
CCFA and celebrity cook Sunny Anderson partner to help IBD patients

The CCFA and Janssen Biotech have partnered with celebrity cook and ulcerative colitis patient Sunny Anderson, along with IBD nutrition expert, Dr. Lindsey Albenberg to help patients manage UC and Crohn's disease.

The Get Your Full Course website comes on the heels of a recent review of interne

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Celgene drug a first of it's kind for Crohn's disease that could replace infusions

2014-10-25 13:49
A new way to treat Crohn's disease with oral medication in the pipeline

A new drug is in the pipeline for Crohn's disease treatment that is expected to move to a third clinical trial in the near future. The drug, known as GED-0301 or Mongersen is an antisense medication taken orally that has been well tolerated and induced remission in sixty-five percent of Crohn's disease patients studied. The medication could replace injections for treating IBD.

The drug manufacturer Celgene (CELG) has released results of an experimental Crohn's disease drug, GED-0301 that could eliminate the need for injections currently used for IBD treatment,

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