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Crohn's and Colitis

Research paves the way for better treatment for children with Crohn's disease

2017-03-22 17:54

Children diagnosed with Crohn's disease could face fewer complications that requires surgery, thanks to new research. It is now possible to predict children who are at risk for developing complications of the bowel disease, which in turns means more personalized Crohn's disease treatment.

The study, published in the journal Lancet, is the result of research from the Crohn's and Colitis Foundation that sought to understand more about pediatric patients diagnosed with Crohn's

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Vitamin D may be more important than known for ulcerative colitis

2017-02-20 19:20

A new study suggests vitamin D may be more important than known for preventing ulcerative colitis flare-ups.

Ulcerative colitis (UC) is an inflammatory bowel disease characterized by inflammation of the large intestine that can frequently relapse after being under control for a period of time.

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This could be why your joints hurt if you have Crohn’s disease

2017-02-10 19:19

New research has uncovered a link between Crohn’s disease and arthritis that can cause joint pain for those affected with the inflammatory bowel disease.

The particular type of pain that was uncovered by researchers is spondyloarthritis that affects the spine and the joints.

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Researchers uncover new focus for IBS treatment

2017-01-31 14:21

Research may have uncovered the cause of irritable bowel syndrome (IBS) that causes suffering to those affected from gas, bloating and intermittent constipation and diarrhea. The finding could mean new treatments that target bacteria in the gut.

Mayo Clinic in Rochester Mn. investigators published findings in the American Journal of Physiology—Gastrointestinal and Liver Physiology.

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Hemp based chewing gum for IBS being tested: 5 things to know

2017-01-25 12:56

AXIM® Biotechnologies has begun Phase 2 clinical trials to find out if a hemp based chewing gum could help those suffering from IBS. Here are 5 things to know about the potential new treatment, should the trial be successful.

The development of the chewing gum, called CanChew is based on delivering cannabinoids that are a group of active substances found in marijuana.

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How mesalamine works to treat ulcerative colitis newly discovered

2017-01-25 09:16

Mesalmine is commonly prescribed for treating ulcerative colitis, but until now researchers were unsure how the medication worked to treat the inflammatory bowel disease.

The prescription has been used for approximately 70 years and for some is a mainstay treatment for the disease. What has been known is that mesalamine quells inflammation in the colon.

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Healthy Diet Recommendations for Crohn's and Colitis from Food Matters

2016-12-06 13:35

During this week’s Crohn’s and Colitis Awareness Week, Tricia Williams, executive chef and founder of Food Matters NYC is sharing how diet can play a key role in treating these Crohn's Disease and Colitis, including food recommendations to help combat the symptoms, as well as foods to avoid to prevent aggravating the condition.

Over 1.4 million Americans suffer from Inflammatory Bowel Disease (IBD) today. The two main types of IBD are Crohn’s & Colitis.

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Lingering food poisoning bacteria linked to cause of Crohn's disease

2016-10-12 12:47

New research suggests the cause of Crohn's disease could be gut bacteria that lingers after a bout of food poisoning has occurred.

The finding could have implications for helping to predict who is at risk for Crohn's disease later in life, according to McMaster University researchers.

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First study shows creeping fat plays a role in IBD

2015-08-05 22:44

New research highlights a potential role of intra abdominal fat in the development and progression of Crohn's disease and ulcerative colitis. This is the first time fat that wraps around the intestines has been linked to ulcerative colitis.

Creeping fat cells found in the abdominal cavity were studied in the lab and shown to promote inflammation associated with IBD.

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How vitamin D might help Crohn's disease

2015-06-16 20:49

Results of a small pilot study suggest vitamin D might help keep Crohn's disease in remission and improve quality of life for people diagnosed with the inflammatory bowel disease.

The finding that is published in the United European Gastroenterology Journal included just 27 participants.

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Researchers test fecal transplant, stem cells for treating Crohn's disease

2015-04-13 19:33

Fecal transplant may be an option for Crohn's disease treatment according to preliminary research conducted among children. A second study recently found stem cells can help repair fistulas that are an all too common complication of Crohn's disease.

In one study fecal transplant that uses feces from a healthy donor resulted in remission of Crohn's disease in seven out of nine children treated.

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Common food ingredient linked to Crohn's, colitis

2015-03-06 10:34

New research suggests emulsifiers that are in the bread you eat every day and in a wide variety of other foods may be contributing to chronic inflammation of the gut that leads to Crohn's disease, ulcerative colitis, metabolic syndrome, type 2 diabetes and more.

Researchers studied the effect of polysorbate 80 and carboxymethylcellulsose in mice to find the emulsifiers promote inflammation.

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Zebrafish provide insights into how Crohn's disease and colitis develop

2015-02-21 12:23

Researchers know that people with inflammatory bowel disease have higher levels of tumor necrosis factor or TNF that is an inflammatory cytokine. Therapy for Crohn's disease and ulcerative colitis is geared toward inhibiting the pro-inflammatory protein to control symptoms. New information from Duke researchers gives insights into epigenetic changes that cause up-regulation of TNF and inflammation associated with the bowel disorders, thanks to zebrafish.

For their study published in the Proceedings of the National Academy of Sciences,.the researchers used zebrafish that are transparent as embryos to visualize changes in the gut that occur in respon

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Global initiative underway to find cause of Crohn's disease

2015-01-22 06:29

International researchers are teaming up to explore what factors lead to Crohn's disease. Many questions remain about the autoimmune disorder that is difficult to manage and incurable. Scientists from Canada and Scotland are coordinating efforts to uncover why Crohn's disease is on the rise. The scientists are looking at families for help understanding IBD.

The hope is that understanding how Crohn's disease develops will lead to better treatments. Crohn's disease has doubled in young people in Scotland every decade for the past 40-years.

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Natural protein could help spare IBD patients from surgery

2015-01-19 21:05

Patients diagnosed with inflammatory bowel disease often develop scarring that leads to narrowing or stricture of the colon. Researchers recently studied a natural protein that might be developed to help limit the amount of intestinal scarring from Crohn's disease and ulcerative colitis, helping spare patients from the need for surgery.

IBD can often lead to repeated surgeries. Quelling inflammation in the colon is a goal of treatment.

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New Crohn's disease damage index tool could help minimize complications

2015-01-12 13:31

Crohn's disease affects everyone differently. Sometimes the damage causes by the form of inflammatory bowel disease is difficult to measure, making it difficult to minimize complications. A new scoring index has now been created by researchers that measures the total damage to the intestines caused by Crohn's disease.

The scoring tool, known as the Lémann Index, was developed by the International Program to Develop New Indexes in Crohn’s Disease (IPNIC) group and is the first tool to take into account the extent

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Friendly yeast gobbling bacteria could help treat Crohn's disease

2015-01-10 10:22

Researchers from the UK and American recently discovered how a yeast gobbling bacteria could help treat Crohn's and other autoimmune diseases. For the first time, scientists have pinpointed a specific immune boosting bacteria that is stimulated when we consume bread,beer and other fermented or yeast containing foods rich in carbohydrate.

The researchers discovered how Bacteroides thetaiotaomicron that is a dominant human gut bacteria could contribute to nourishing the cells in the intestine to provide a protective effect against Cr

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Obesity clearly linked to Crohn's and other autoimmune diseases

2014-11-10 12:46

New research suggests obesity could be a major contributor to Crohn's disease, multiple sclerosis and other autoimmune diseases that are the result of the the immune system attacking the body. The result of the investigation shows obesity could also prolong the effects of autoimmune diseases that also appear to be triggered by additional environmental factors.

What the researchers from Tel Aviv University found is that obesity creates a "pro-inflammatory" environment that can trigger Crohn's disease, MS and other autoimmune diseases in addition to hamper

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Sleep and ulcerative colitis have something in common

2014-11-05 21:27

A recent investigation from researchers at Massachusetts General Hospital suggests sleep duration may be an important factor when it comes to both preventing and managing ulcerative colitis that affects one million people worldwide.

Results of a new investigation suggests sleeping too little might increase a person's risk of developing UC in addition to causing flare-up.

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CCFA partners with celebrity cook to help Crohn's, colitis patients

2014-10-26 10:46

The CCFA and Janssen Biotech have partnered with celebrity cook and ulcerative colitis patient Sunny Anderson, along with IBD nutrition expert, Dr. Lindsey Albenberg to help patients manage UC and Crohn's disease.

The Get Your Full Course website comes on the heels of a recent review of interne

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Celgene drug a first of it's kind for Crohn's disease that could replace infusions

2014-10-25 13:49

A new drug is in the pipeline for Crohn's disease treatment that is expected to move to a third clinical trial in the near future. The drug, known as GED-0301 or Mongersen is an antisense medication taken orally that has been well tolerated and induced remission in sixty-five percent of Crohn's disease patients studied. The medication could replace injections for treating IBD.

The drug manufacturer Celgene (CELG) has released results of an experimental Crohn's disease drug, GED-0301 that could eliminate the need for injections currently used for IBD treatment,

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Bone marrow transplant a potential cure for Crohn's disease

2014-10-22 05:16

Fred Hutchinson Cancer Research investigators are currently enrolling patients in a clinical trial that could potentially lead to a cure for moderate to severe Crohn's disease that has failed other therapies including surgery. The treatment wipes out the patient's immune system and then builds a new one to quell inflammation in the intestines.

So far, the results look promising and researchers say it might be possible to "cure" Crohn's disease.

How bone marrow transplant could help Crohn's disease

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Crohn's and colitis diet information on the internet could mislead

2014-10-14 13:41

Because there is so much conflicting information, patients with IBD often turn to forums and the internet to find out what diet can help Crohn's disease and colitis. Researchers recently reviewed dietary advice found on websites in an effort to determine what sort of diets are advocated for patients with IBD. The question remains whether the diets help or harm.

The conclusion of the investigation is that there is a dire need for studies about how specific foods might impact gut bacteria to influence the course of IBD,Some diets are restrictive, conflictin

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Crohn's disease and colitis bloating: When to see your doctor

2014-10-08 22:24

Anyone can experience belly bloating but for people diagnosed with Crohn's disease or colitis the condition can be especially painful and even worrisome. Understanding how to manage bloating if you have IBD and when it is important to see your doctor can help lower your chances of complications and definitely make you more comfortable.

What causes bloating and when should you see your doctor?

Bloating and active IBD

Sometimes bloating is worse when Crohn's disease or UC is active.

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Does fecal transplant help Crohn's disease or colitis?

2014-10-03 12:42

There has been some research suggesting fecal microbial transplant (FMT) might be a treatment for Crohn's disease and ulcerative colitis. In a first clinical trial published in Gastroenterology and Endocrinology News, scientists report mixed results.

The first clinical trial shows FMT didn't work any better than placebo, despite anecdotal reports of FMT Crohn's disease "cures" that can be found on the internet.

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Microneedle pill could eliminate injections for diabetes, Crohn's disease and more

2014-10-01 21:37

MIT researchers are working on a way to eliminate the need for injectable medications with a new drug-delivery capsule that contains microneedles. The capsule, when tested, worked better than insulin injections and could work even better for Crohn's and arthritis treatments.

The finding could mean no more insulin injections for diabetics and it could also mean patients with cancer, Crohn's disease and other autoimmune disorders could swallow a capsule to obtain antibod

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Crab, shrimp and lobster could offer Crohn's disease help

2014-10-01 18:16

Our crustacean friends might be able to help with prevention and treatment of inflammatory bowel diseases including Crohn's and ulcerative colitis. Researchers recently discovered the shells of shrimp, crab and lobster contain microparticles with anti-inflammatory properties that could provide new and inexpensive IBD treatment.

Yoshimi Shibata, Ph.D., professor of biomedical science in the Charles E.

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Crohn's disease and colitis rates increase in Canada, highlighting need for a cure

2014-09-26 12:01

In a first study researchers have found rates of Crohn's disease and colitis have significantly increased in Ontario, Canada. The finding highlights the need to find a cure for IBD that places a significant burden on children and adults diagnosed with the disease, as well as the health care system.

Research published this month highlights the growing prevalence of Crohn's disease and colitis in Canada.

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Crohn's disease skin problems: When to see your doctor

2014-09-25 20:10

Crohn's disease and ulcerative colitis can also affect your skin. When should you see your doctor for treatment and what does it mean?

If you have Crohn's disease or ulcerative colitis you could be susceptible to other health problems that are worth noting. It's important to know when to see the doctor.

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