The Pill Increases Brain Size, Memory Area

2010-08-20 00:18

Women who take the Pill may be getting more than protection against pregnancy. A new study indicates that this popular form of contraception can also increase brain size, including the areas associated with memory and social skills.

Brain size differences in men and women

When it comes to brain size, research indicates there is a difference between males and females in specific areas of the brain. Generally, males have a larger amygdala (memory and emotions) and hypothalamus (metabolic processes), while females have a larger caudate (memory and learning) and hippocampus (long-term memory and spatial navigation). Overall, women have a greater percentage of gray matter, while men have a higher percentage of white matter and cerebrospinal fluid.

The new study, which appears in the journal Brain Research, is the first to evaluate the impact of hormonal contraceptives on brain structure. Participants included 28 women, half of whom were taking the Pill, and 14 men. Scientists took high-resolution images of the subjects’ brains and compared the results.

The women who were not taking the contraceptive were scanned more than once to account for fluctuations in hormone levels that normally occur. Overall, the investigators found that women who took the Pill showed an increase in brain size of about 3 percent. This increase was the same regardless of which formulation of the contraceptive the women took.


According to Belinda Pletzer of Salzburg University, the hormones in the Pill clearly had a “tremendous effect” on the brains of the women. The increase in brain size was observed in regions already known to be larger in women when compared with men. Pletzer noted that “Larger volumes of a brain area could lead to an improvement of the functions this area is responsible for.”


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