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Dog Health

Evolutionary Event Underlying Origin Of Dogs With Short Legs

2009-07-17 11:45

A single evolutionary event appears to explain the short, curved legs that characterize all of today’s dachshunds, corgis, basset hounds and at least 16 other breeds of dogs, a team led by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, reported today. In addition to what it reveals about short-legged dogs, the unexpected discovery provides new clues about how physical differences may arise within species and suggests new approaches to understanding a form of human dwarfism.

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FDA Approved First Dog Cancer Treatment Drug

2009-06-04 12:14

The U.S. Food and Drug Administration today announced the approval of Palladia (toceranib phosphate), the first drug developed specifically for the treatment of cancer in dogs.

Palladia is approved to treat canine cutaneous (skin-based) mast cell tumors, a type of cancer responsible for about 1 out of 5 cases of canine skin tumors. The drug is approved to treat the tumors with or without regional lymph node involvement.

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Gene Delivery System Targets Blood Vessels In Dogs With Cancer

2009-03-30 12:56

In a preliminary study of pet dogs with naturally occurring cancer, researchers have developed a way to target delivery of a gene to tumor blood vessels, where the gene product damages the vessels, disrupting blood flow to the tumors but not to the surrounding tissue. The delivery method was well tolerated, and in some dogs, the size of tumors decreased or remained stable. This study provides valuable information that may aid in the design of future clinical trials.

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