Vitamin D reported to clear Alzheimer's plaques
LOS ANGELES, CA – Amyloid beta is the main component of plaques associated with Alzheimer’s disease. Now, UCLA researchers have discovered intracellular mechanisms regulated by Vitamin D3, which may stimulate the immune system to clear the brain of this substance. They published their findings on March 6 in the Journal of Alzheimer's Disease.
The researchers noted that they had conducted a previous study that demonstrated that specific types of immune cells in Alzheimer's patients may respond to therapy with Vitamin D3 and curcumin, a chemical found in turmeric spice. These substances stimulated the immune system to clear amyloid beta; however, the researchers did not know the underlying mechanism.
"This new study helped clarify the key mechanisms involved, which will help us better understand the usefulness of vitamin D3 and curcumin as possible therapies for Alzheimer's disease," noted study author Dr. Milan Fiala, a researcher at the David Geffen School of Medicine at UCLA and the Veterans Affairs Greater Los Angeles Healthcare System.